TRIM21 Peptide (AAP38248)

Data Sheet
 
Sku AAP38248
Old sku AAPP23102
Price $99.00
Name TRIM21 Peptide (AAP38248)
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Size 100 ug
Gene TRIM21
Alias symbols RNF81, RO52, SSA, SSA1
Gene id 6737
Description of target TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM21 is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus.This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot id P19474
Protein accession num NP_003132
Nucleotide accession num NM_003141
Protein size 475 amino acids
Molecular weight 54kDa
Application WB
Partner proteins NIF3L1,TRIM21,TROVE2,USP4,YWHAZ,CUL1,IRF8,NCOA1,NCOA3,NIF3L1,SKP1,SKP2,TRIM21,UBC,USP19,USP4
Quality control The peptide is characterized by mass spectroscopy
Key reference Yamochi,T., (2008) Biochem. Biophys. Res. Commun. 370 (1), 195-199
Description This is a synthetic peptide designed for use in combination with anti-TRIM21 antibody (Catalog #: ARP38248_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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