Sku |
AAP35097 |
Old sku |
AAPP06328 |
Price |
$99.00 |
Name |
KCNN3 Peptide (AAP35097) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
KCNN3 |
Alias symbols |
SK3, hSK3, SKCA3, KCa2.3 |
Gene id |
3782 |
Description of target |
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. |
Swissprot id |
Q9UGI6 |
Protein accession num |
NP_002240 |
Nucleotide accession num |
NM_002249 |
Protein size |
736 amino acids |
Molecular weight |
81kDa |
Application |
IHC, WB |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Kolski-Andreaco,A., et al., (2004) J. Biol. Chem. 279 (8), 6893-6904 |
Description |
This is a synthetic peptide designed for use in combination with anti-KCNN3 antibody (Catalog #: ARP35097_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |