ARID4A Peptide (AAP33088)

Data Sheet
 
Sku AAP33088
Old sku AAPP04121
Price $99.00
Name ARID4A Peptide (AAP33088)
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Size 100 ug
Gene ARID4A
Alias symbols RBP1, RBBP1, RBP-1, RBBP-1
Gene id 5926
Description of target ARID4A encodes a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described.
Swissprot id P29374
Protein accession num NP_002883
Nucleotide accession num NM_002892
Protein size 1257 amino acids
Molecular weight 143kDa
Application WB
Partner proteins BRMS1,EID1,HDAC1,HDAC2,HDAC3,SIN3A,ING2,RB1,RBL1
Quality control The peptide is characterized by mass spectroscopy
Key reference Meehan,W.J., et al., (2004) J. Biol. Chem. 279 (2), 1562-1569
Description This is a synthetic peptide designed for use in combination with anti-ARID4A antibody (Catalog #: ARP33088_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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