APEX1 Peptide (AAP32651)

Data Sheet
 
Sku AAP32651
Old sku AAPP03661
Price $99.00
Name APEX1 Peptide (AAP32651)
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Size 100 ug
Gene APEX1
Alias symbols APE, APX, APE1, APEN, APEX, HAP1, REF1
Gene id 328
Description of target Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells.
Swissprot id P27695
Protein accession num NP_542379
Nucleotide accession num NM_080648
Protein size 318 amino acids
Molecular weight 35kDa
Application IHC, WB
Partner proteins CDKN1A,MUTYH,TP53,ANP32A,ANP32C,APEX1,CSNK2A1,DCTN1,EP300,FEN1,GZMA,HDAC1,HIF1A,HMGB2,HNRNPL,HSPA1A,MUTYH,NME1,NXF2,PCNA,POLB,SET,TP53,TXN,UBE2I,XRCC1,XRCC6,ANP32A,FEN1,HIF1A,HNRNPL,MUTYH,PCNA,SET,TP53,XRCC1,XRCC5
Quality control The peptide is characterized by mass spectroscopy
Key reference Ding,S.Z., et al., (2004) Gastroenterology 127 (3), 845-858
Description This is a synthetic peptide designed for use in combination with anti-APEX1 antibody (Catalog #: ARP32651_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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