Sku |
AAP32651 |
Old sku |
AAPP03661 |
Price |
$99.00 |
Name |
APEX1 Peptide (AAP32651) |
Purchase info |
To purchase this peptide:
- Copy peptide sku
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|
Size |
100 ug |
Gene |
APEX1 |
Alias symbols |
APE, APX, APE1, APEN, APEX, HAP1, REF1 |
Gene id |
328 |
Description of target |
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. |
Swissprot id |
P27695 |
Protein accession num |
NP_542379 |
Nucleotide accession num |
NM_080648 |
Protein size |
318 amino acids |
Molecular weight |
35kDa |
Application |
IHC, WB |
Partner proteins |
CDKN1A,MUTYH,TP53,ANP32A,ANP32C,APEX1,CSNK2A1,DCTN1,EP300,FEN1,GZMA,HDAC1,HIF1A,HMGB2,HNRNPL,HSPA1A,MUTYH,NME1,NXF2,PCNA,POLB,SET,TP53,TXN,UBE2I,XRCC1,XRCC6,ANP32A,FEN1,HIF1A,HNRNPL,MUTYH,PCNA,SET,TP53,XRCC1,XRCC5 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Ding,S.Z., et al., (2004) Gastroenterology 127 (3), 845-858 |
Description |
This is a synthetic peptide designed for use in combination with anti-APEX1 antibody (Catalog #: ARP32651_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |