Sku |
AAP30587 |
Old sku |
AAPP01250 |
Price |
$99.00 |
Name |
OAS1 Peptide - C-terminal region (AAP30587) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
OAS1 |
Alias symbols |
IFI-4, OIAS, OIASI |
Gene id |
4938 |
Description of target |
OAS1 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Mutations in this gene have been associated with host susceptibility to viral infection.This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. |
Swissprot id |
P00973 |
Protein accession num |
NP_058132 |
Nucleotide accession num |
NM_016816 |
Protein size |
400 amino acids |
Molecular weight |
46kDa |
Application |
IHC, WB |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Phosri,C., Mycol. Res. 111 (PT 3), 275-286 (2007) |
Description |
This is a synthetic peptide designed for use in combination with anti-OAS1 antibody (Catalog #: AVARP20004_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |