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Datasheets/Manuals | Printable datasheet for anti-SCP2 (ARP56538_P050) antibody |
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Tested Species Reactivity | Human |
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Predicted Species Reactivity | Human, Mouse, Rat, Guinea Pig, Horse, Zebrafish |
Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Clonality | Polyclonal |
Host | Rabbit |
Application | WB |
Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human SCP2 |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rat: 100%; Zebrafish: 93% |
Peptide Sequence | Synthetic peptide located within the following region: NHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILA |
Concentration | 0.5 mg/ml |
Blocking Peptide | For anti-SCP2 (ARP56538_P050) antibody is Catalog # AAP56538 (Previous Catalog # AAPP34135) |
Reference | Stanley,W.A., (2007) Arch. Biochem. Biophys. 461 (1), 50-58 |
Gene Symbol | SCP2 |
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Gene Full Name | Sterol carrier protein 2 |
Alias Symbols | NLTP, SCOX, SCPX, SCP-2, SCP-X, NSL-TP, SCP-CHI |
NCBI Gene Id | 6342 |
Protein Name | Non-specific lipid-transfer protein |
Description of Target | SCP2 protein is thought to be an intracellular lipid transfer protein. SCP2 is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis.This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined. |
Uniprot ID | Q6NXF4 |
Protein Accession # | NP_001007099 |
Nucleotide Accession # | NM_001007098 |
Protein Size (# AA) | 322 |
Molecular Weight | 35kDa |
Protein Interactions | TRIP13; UBC; PEX5; MPLKIP; MRRF; SUGP1; MRPS28; TBL2; SRRM2; RAB31; SEPT9; TIMM44; ECI2; SCO2; AGPS; STX7; UBL4A; VDAC3; VDAC2; RRBP1; RBMS1; NDUFA7; IDH3G; HSD17B4; ACAA1; RAB8A; ELAVL1; CACNA1A; ACAA2; EHHADH; CAV1; ACOX1; PITPNA; |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "SCP2 Antibody - middle region (ARP56538_P050)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Guinea Pig, Horse, Zebrafish".
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How long will it take to receive "SCP2 Antibody - middle region (ARP56538_P050)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
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What buffer format is "SCP2 Antibody - middle region (ARP56538_P050)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "SCP2 Antibody - middle region (ARP56538_P050)"?
This target may also be called "NLTP, SCOX, SCPX, SCP-2, SCP-X, NSL-TP, SCP-CHI" in publications.
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What is the shipping cost for "SCP2 Antibody - middle region (ARP56538_P050)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "SCP2 Antibody - middle region (ARP56538_P050)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "SCP2 Antibody - middle region (ARP56538_P050)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "35kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "SCP2 Antibody - middle region (ARP56538_P050)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "SCP2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "SCP2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "SCP2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "SCP2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "SCP2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "SCP2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.