SART3 Antibody - N-terminal region : FITC (ARP39128_T100-FITC)

Catalog No: ARP39128_T100-FITC

Size:100ul

Product Info

• Predicted Species Reactivity: Human, Rat, Dog, Guinea Pig, Horse, Pig
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: FITC: Fluorescein Isothiocyanate
• Application: IHC, WB
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SART3
• Predicted Homology Based on Immunogen Sequence: Dog: 77%; Guinea Pig: 79%; Horse: 79%; Human: 100%; Pig: 86%; Rat: 79%
• Peptide Sequence: Synthetic peptide located within the following region: TSASEPEAESKAGPKADGEEDEVKAARTRRKVLSRAVAAATYKTMGPAWD
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-SART3 (ARP39128_T100-FITC) antibody is Catalog # AAP39128 (Previous Catalog # AAPP21237)
• Sample Type Confirmation:

  SART3 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

• Reference: Liu,Y.,(2002) J. Biol. Chem. 277 (26), 23854-23863

Target Info

• Gene Symbol: SART3
• Gene Full Name: Squamous cell carcinoma antigen recognized by T cells 3
• Alias Symbols: P100, p110, DSAP1, TIP110, p110(nrb), RP11-13G14
• NCBI Gene Id: 9733
• Protein Name: Squamous cell carcinoma antigen recognized by T-cells 3
• Description of Target: SART3 is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. SART3 is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This protein is thought to be involved in the regulation of mRNA splicing.
• Uniprot ID: Q15020-2
• Protein Accession #: AAK69347
• Nucleotide Accession #: NM_014706
• Protein Size (# AA): 364
• Molecular Weight: 40kDa
• Protein Interactions: APBB1; PRPF3; Usp15; AMOT; SF3B1; NUP160; LRPPRC; THRAP3; BCLAF1; VARS; UBC; SUMO2; RAB1A; NEFM; IARS; HIF1A; DSG2; DHX9; MEPCE; HIST2H2BE; HIST2H2AC; RNF2; BMI1; RUFY1; NRBP1; PSME4; AKAP2; COPS5; NUP50; POP7; ARHGEF10; PSMB3; PSMA5; PSMA3; POLR2H; CAST;