Catalog No: ARP46087_P050
Price: $0.00
SKU
ARP46087_P050
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Datasheets/ManualsPrintable datasheet for anti-RFC4 (ARP46087_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human RFC4
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 86%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 93%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: DKLEAVVKDLIDEGHAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDK
Concentration0.5 mg/ml
Blocking PeptideFor anti-RFC4 (ARP46087_P050) antibody is Catalog # AAP46087 (Previous Catalog # AAPP26949)
Sample Type Confirmation

RFC4 is supported by BioGPS gene expression data to be expressed in 721_B

Subunit4
ReferenceGupte,R.S., (2005) Cell Cycle 4 (2), 323-329
Gene SymbolRFC4
Gene Full NameReplication factor C (activator 1) 4, 37kDa
Alias SymbolsA1, RFC37
NCBI Gene Id5984
Protein NameReplication factor C subunit 4
Description of TargetThe elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template.The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.
Uniprot IDP35249
Protein Accession #NP_002907
Nucleotide Accession #NM_002916
Protein Size (# AA)363
Molecular Weight40kDa
Protein InteractionsRNF41; UBC; RFC5; PCNA; TP53; SUMO2; RPA3; RPA2; RPA1; RNF2; C14orf166; RTCB; RPL26L1; DIMT1; NELFB; EDC4; IGF2BP3; EIF2B2; EIF2B3; YBX3; QARS; NMT1; HNRNPM; MRE11A; ILF2; HNRNPU; FLII; FKBP3; EPRS; DHX9; DDX1; ABCF1; PARK2; TARDBP; MPG; RFC2; MYC; FN1; P
  1. What is the species homology for "RFC4 Antibody - middle region (ARP46087_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit".

  2. How long will it take to receive "RFC4 Antibody - middle region (ARP46087_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "RFC4 Antibody - middle region (ARP46087_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "RFC4 Antibody - middle region (ARP46087_P050)"?

    This target may also be called "A1, RFC37" in publications.

  5. What is the shipping cost for "RFC4 Antibody - middle region (ARP46087_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "RFC4 Antibody - middle region (ARP46087_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "RFC4 Antibody - middle region (ARP46087_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "40kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "RFC4 Antibody - middle region (ARP46087_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "RFC4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "RFC4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "RFC4"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "RFC4"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "RFC4"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "RFC4"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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