RESISTIN Recombinant Protein (OPSA11047)

Catalog No: OPSA11047 (Formerly GWB-F4A137)

Size:25UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: Lyophilized. 10mM Sodium Citrate
• Application: Enzyme-linked immunosorbent assay|Functional assay|Western blot
• Additional Information: Activity: Determined by its ability to stimulate lipolysis in cultured human adipocytes.
  Approx Protein Conc: Total protein concentration 0.1mg/ml after reconstitution
  Buffer solution: 10mM Sodium Citrate
  Endotoxin Level: < 1EU/ug
  Label Protein Molar Ratio: Purified recombinant resistin expressed in E.coli.
  Preservative: None present
• Reconstitution and Storage: -20°C
• Predicted Homology Based on Immunogen Sequence: Human
• Purification: Purified recombinant resistin expressed in E.coli
• Concentration: 0.1 mg/ml
• Purity: >98% by SDS PAGE and HPLC analysis.
• Specificity: Human resistin, a disulfide-linked homodimeric protein otherwise known as adipose tissue-specific secretory factor, is an adipose-derived hormone and member of the resistin/FIZZ family, implicated as a suppressor of the ability of insulin to reduce blood sugar, and to play a role in type 2 diabetes and obesity.
  Studies have shown that resistin is involved in an increase in the transcription/expression of many pro-inflammatory cytokines, including interleukin-1,-6 and -12, and also upregulates vascular cell-adhesion molecule-1 (VCAM-1), intracellular adhesion molecule-1 (ICAM-1), and monocyte chemotactic protein-1 (MCP-1/CCL2).
  
• Application Info: ELISA:    0.2 - 0.4ng/well
  Western Blotting:    1.5 - 3.0ng/lane
  

Target Info

• Gene Symbol: RETN
• Alias Symbols: ADSF, RSTN, XCP1, FIZZ3, RETN1
• NCBI Gene Id: 56729
• Protein Name: Resistin
• Description of Target: RECOMBINANT HUMAN RESISTIN
  
• Uniprot ID: Q9HD89
• Protein Accession #: NP_065148.1
• Protein Size (# AA): Recombinant
• Molecular Weight: 19.5kD