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RAD23A Antibody - middle region (ARP42211_T100)
Datasheets/Manuals | Printable datasheet for anti-RAD23A (ARP42211_T100) antibody |
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Tested Species Reactivity | Human |
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Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit |
Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Clonality | Polyclonal |
Host | Rabbit |
Application | IHC, WB |
Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human RAD23A |
Purification | Protein A purified |
Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100% |
Peptide Sequence | Synthetic peptide located within the following region: GIPGSPEPEHGSVQESQVSEQPATEAAGENPLEFLRDQPQFQNMRQVIQQ |
Concentration | 1.0 mg/ml |
Blocking Peptide | For anti-RAD23A (ARP42211_T100) antibody is Catalog # AAP42211 (Previous Catalog # AAPP24634) |
Sample Type Confirmation | RAD23A is supported by BioGPS gene expression data to be expressed in Jurkat |
Reference | Ju,D. (2006) Biochem. Biophys. Res. Commun. 341 (2), 648-652 |
Publications | USF-1 is critical for maintaining genome integrity in response to UV-induced DNA photolesions. PLoS Genet. 8, e1002470 (2012). 22291606 |
Description |
Gene Symbol | RAD23A |
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Gene Full Name | RAD23 homolog A (S. cerevisiae) |
Alias Symbols | HR23A, HHR23A |
NCBI Gene Id | 5886 |
Protein Name | UV excision repair protein RAD23 homolog A |
Description of Target | RAD23A is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. |
Uniprot ID | P54725 |
Protein Accession # | NP_005044 |
Nucleotide Accession # | NM_005053 |
Protein Size (# AA) | 363 |
Molecular Weight | 40kDa |
Protein Interactions | USP25; ZBTB44; TRIP6; TRAF5; TRAF2; ZBTB8A; ANKRD40; FAM188A; TRIM54; NGLY1; CEP250; CEP76; UBC; SHFM1; vpr; XPC; DCTPP1; OGFOD1; UBA6; UBE2R2; TRNT1; HERC4; NT5C2; FKBP9; PCNA; HEXA; CDC34; GNPDA1; GTF3C4; USP5; WARS; TBCE; PYGL; PARP1; SH3RF2; PARK2; SQ |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "RAD23A Antibody - middle region (ARP42211_T100)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit".
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How long will it take to receive "RAD23A Antibody - middle region (ARP42211_T100)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
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What buffer format is "RAD23A Antibody - middle region (ARP42211_T100)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "RAD23A Antibody - middle region (ARP42211_T100)"?
This target may also be called "HR23A, HHR23A" in publications.
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What is the shipping cost for "RAD23A Antibody - middle region (ARP42211_T100)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "RAD23A Antibody - middle region (ARP42211_T100)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "RAD23A Antibody - middle region (ARP42211_T100)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "40kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "RAD23A Antibody - middle region (ARP42211_T100)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "RAD23A"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "RAD23A"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "RAD23A"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "RAD23A"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "RAD23A"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "RAD23A"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.