MAGEA8 Antibody - N-terminal region (ARP42233_P050)

Catalog No: ARP42233_P050

WB Suggested Anti-MAGEA8 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Placenta

Rabbit Anti-MAGEA8 Antibody
Catalog Number: ARP42233
Paraffin Embedded Tissue: Human Lung
Cellular Data: Alveolar cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: IHC, WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAGEA8
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human: 100%
• Peptide Sequence: Synthetic peptide located within the following region: EEVTDSGSPSPPQSPEGASSSLTVTDSTLWSQSDEGSSSNEEEGPSTSPD
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-MAGEA8 (ARP42233_P050) antibody is Catalog # AAP42233 (Previous Catalog # AAPP24656)
• Reference: Lee,J.H., (2000) Mol. Cells 10 (6), 647-653

Target Info

• Gene Symbol: MAGEA8
• Gene Full Name: Melanoma antigen family A, 8
• Alias Symbols: CT1.8, MAGE8
• NCBI Gene Id: 4107
• Protein Name: Melanoma-associated antigen 8
• Description of Target: MAGEA8 is a member of the MAGEA family. The members of this family with 50 to 80% sequence identity to each other. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
• Uniprot ID: Q9BUN9
• Protein Accession #: NP_005355
• Nucleotide Accession #: NM_005364
• Protein Size (# AA): 318
• Molecular Weight: 35kDa
• Protein Interactions: MTUS2; PKD2; MAGEB4; LMO2; BEX5; LXN; GCA; UBE3A; UBC;