Catalog No: ARP41735_P050
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ARP41735_P050
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Datasheets/ManualsPrintable datasheet for anti-KRT2 (ARP41735_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human KRT2A
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 79%; Dog: 100%; Guinea Pig: 79%; Horse: 88%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 79%; Rat: 81%
Peptide SequenceSynthetic peptide located within the following region: EVKAQYEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELN
Concentration0.5 mg/ml
Blocking PeptideFor anti-KRT2 (ARP41735_P050) antibody is Catalog # AAP41735 (Previous Catalog # AAPP24378)
Enhanced Validation
Relative Expression (Western Blot) Avivasheild
ReferenceBloor,B.K., (2003) Am. J. Pathol. 162 (3), 963-975
Gene SymbolKRT2
Gene Full NameKeratin 2
Alias SymbolsK2e, KRTE, CK-2e, KRT2A, KRT2E
NCBI Gene Id3849
Protein NameKeratin, type II cytoskeletal 2 epidermal
Description of TargetKRT2A is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma.The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Uniprot IDP35908
Protein Accession #NP_000414
Nucleotide Accession #NM_000423
Protein Size (# AA)639
Molecular Weight65 kDa
Protein InteractionsKRT40; KRT38; KRT31; KRT19; KRT13; Fbxl16; LGR4; EED; ADRB2; PAN2; Nphp4; IQCB1; VCAM1; UBC; FN1; EIF4A3; MAGOH; KRT10; KRT1; UBASH3B; SHC1; PIK3R2; INPPL1; GRB2; EPS15; CRK; AP2M1; CBL; CAND1; DCUN1D1; COPS5; COPS6; CUL1; CUL2; CUL3; CUL4A; CUL4B; CUL5;
  1. What is the species homology for "KRT2A Antibody - middle region (ARP41735_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit".

  2. How long will it take to receive "KRT2A Antibody - middle region (ARP41735_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "KRT2A Antibody - middle region (ARP41735_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "KRT2A Antibody - middle region (ARP41735_P050)"?

    This target may also be called "K2e, KRTE, CK-2e, KRT2A, KRT2E" in publications.

  5. What is the shipping cost for "KRT2A Antibody - middle region (ARP41735_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "KRT2A Antibody - middle region (ARP41735_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "KRT2A Antibody - middle region (ARP41735_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "65 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "KRT2A Antibody - middle region (ARP41735_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "KRT2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "KRT2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "KRT2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "KRT2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "KRT2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "KRT2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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