- Description of Target:
- SOX18 a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.
- Gene Symbol:
- Official Gene Full Name:
- SRY (sex determining region Y)-box 18
- NCBI Gene Id:
- Alias Symbols:
- Tissue Tool:
- Find tissues and cell lines supported by DNA array analysis to express SOX18.
- RNA Seq:
- Find tissues and cell lines supported by RNA-seq analysis to express SOX18.
- Swissprot Id:
- Protein Accession #:
- Nucleotide Accession #:
- Protein Name:
- Transcription factor SOX-18
- Protein Size (# AA):
- Molecular Weight:
- Protein Interactions:
- GKAP1; MECP2; MEF2C; HMGB1;
- The immunogen is a synthetic peptide directed towards the middle region of human SOX18
- Product Format:
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
- Protein A purified
- Complete computational species homology data:
- Anti-SOX18 (ARP33057_T100)
- Predicted Homology Based on Immunogen Sequence:
- Cow: 92%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 85%; Rat: 85%
- Species Reactivity:
- Cow; Dog; Guinea Pig; Human; Mouse; Rat
- Datasheets / Downloads:
- Printable datasheet for anti-SOX18 (ARP33057_T100) antibody
- Peptide Sequence:
- Synthetic peptide located within the following region: GSARAFRELPPLGAEFDGLGLPTPERSPLDGLEPGEAAFFPPPAAPEDCA
- Blocking Peptide:
- For anti-SOX18 (ARP33057_T100) antibody is Catalog # AAP33057 (Previous Catalog # AAPP04086)
- Target Reference:
- Irrthum,A., et al., (2003) Am.J.Hum.Genet.72(6),1470-1478
- Reconstitution and Storage:
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Aviva Systems Biology is the original manufacturer of this SOX18 antibody (ARP33057_T100)
Click here to view the SOX18 antibody Western Blot Protocol
Product Datasheet Link: SOX18 antibody (ARP33057_T100)
WB Suggested Anti-SOX18 Antibody Titration: 2.0ug/ml
Positive Control: Jurkat
Western Blot image:
Description of Target: SOX18 a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.
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