- Description of Target:
- GNB2L1 seems to bind protein kinase C acting as an intracellular receptor to anchor the activated PKC to the cytoskeleton. GNB2L1 may be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and ITGB1, GNB2L1 serves as a platform for SRC activation or inactivation. GNB2L1 may play an important role in the developing brain and neuronal differentiation.
- Gene Symbol:
- Official Gene Full Name:
- Guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
- NCBI Gene Id:
- Alias Symbols:
- Gnb2-rs1; H12.3; HLC-7; PIG21; RACK1
- Tissue Tool:
- Find tissues and cell lines supported by DNA array analysis to express GNB2L1.
- RNA Seq:
- Find tissues and cell lines supported by RNA-seq analysis to express GNB2L1.
- Swissprot Id:
- Protein Accession #:
- Nucleotide Accession #:
- Protein Name:
- Guanine nucleotide-binding protein subunit beta-2-like 1
- Protein Size (# AA):
- Molecular Weight:
- IHC, WB
- beta-2-like 1
- Protein Interactions:
- MKRN2; LARP4B; HUWE1; UBC; SUMO2; HIF1A; STAU1; TARDBP; ADRB2; PRKCB; TRIM45; RNF2; EZH2; BMI1; SUZ12; rev; PTOV1; RPS8; RPS6; RPS5; RPS3A; RPS27L; EIF3K; SYNCRIP; DYNLL1; RPS3; RPSA; EIF3E; DYNC1LI2; RPS9; RPS27; RPS21; RPS20; RPS18; RPS16; RPS13; RPS12;
- The immunogen is a synthetic peptide directed towards the N terminal region of human GNB2L1
- Product Format:
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
- Affinity Purified
- Complete computational species homology data:
- Anti-GNB2L1 (ARP40624_P050)
- Predicted Homology Based on Immunogen Sequence:
- Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Yeast: 100%; Zebrafish: 100%
- Species Reactivity:
- Cow; Dog; Guinea Pig; Human; Mouse; Rabbit; Rat; Sheep; Yeast; Zebrafish
- Datasheets / Downloads:
- Printable datasheet for anti-GNB2L1 (ARP40624_P050) antibody
- Peptide Sequence:
- Synthetic peptide located within the following region: ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI
- Blocking Peptide:
- For anti-GNB2L1 (ARP40624_P050) antibody is Catalog # AAP40624 (Previous Catalog # AAPP22384)
- Target Reference:
- Parent,A., (2008) Traffic 9 (3), 394-407
- Reconstitution and Storage:
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Aviva Systems Biology is the original manufacturer of this GNB2L1 antibody (ARP40624_P050)
Click here to view the GNB2L1 antibody Western Blot Protocol
Product Datasheet Link: GNB2L1 antibody (ARP40624_P050)
WB Suggested Anti-GNB2L1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Transfected 293T
Western Blot image:
Description of Target: GNB2L1 seems to bind protein kinase C acting as an intracellular receptor to anchor the activated PKC to the cytoskeleton. GNB2L1 may be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and ITGB1, GNB2L1 serves as a platform for SRC activation or inactivation. GNB2L1 may play an important role in the developing brain and neuronal differentiation.
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