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CRK antibody - C-terminal region (ARP30416_P050)

Receive a free blocking peptide (AAP30416) when you purchase this antibody. Use the promotion code 'freepeptide' when placing your order.
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Description of Target:
This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
Gene Symbol:
Official Gene Full Name:
V-crk sarcoma virus CT10 oncogene homolog (avian)
NCBI Gene Id:
Alias Symbols:
CRKII; p38
Tissue Tool:
Find tissues and cell lines supported to express CRK.
Protein Accession #:
Nucleotide Accession#:
Swissprot Id:
Protein Name:
Adapter molecule crk
Protein Size (# AA):
Molecular Weight:
Partner Proteins:
Product Format:
Lyophilized powder
Complete computational species homology data:
CRK antibody - C-terminal region (ARP30416_P050)
Predicted Homology Based on Immunogen Sequence:
African clawed frog: 100%; Bovine: 100%; Dog: 100%; Guinea pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Chicken: 90%
Species Reactivity:
Bovine, Dog, Guinea pig, Horse, Human, Mouse, Rat
Datasheets / Downloads:
Printable datasheet for
anti-CRK antibody
- ARP30416_P050
Peptide Sequence:
Synthetic peptide located within the following region: IPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEPGPYAQPSVNTPLP
Blocking Peptide:
For anti-CRK antibody is Catalog # AAP30416
Key Reference:
Reconstitution and Storage:
Add 50 ul of distilled water. Final anti-CRK antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
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