Catalog No: ARP45918_T100
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ARP45918_T100
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Datasheets/ManualsPrintable datasheet for anti-SIK1 (ARP45918_T100) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Additional InformationIHC Information: Jurkat cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%.
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human SNF1LK
PurificationProtein A purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 93%; Guinea Pig: 85%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 90%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: MVIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTK
Concentration1.0 mg/ml
Blocking PeptideFor anti-SIK1 (ARP45918_T100) antibody is Catalog # AAP45918 (Previous Catalog # AAPS17111)
Enhanced Validation
Relative Expression (Western Blot) Avivasheild
ReferenceNishimura,Y., (1999) Biochem. Biophys. Res. Commun. 254 (1), 21-26
Gene SymbolSIK1
Gene Full NameSalt-inducible kinase 1
Alias SymbolsMSK, SIK, DEE30, SIK-1, SIK1B, SNF1LK
NCBI Gene Id150094
Protein NameSerine/threonine-protein kinase SIK1
Description of TargetSNF1LK play a transient role during the earliest stages of myocardial cell differentiation and/or primitive chamber formation and may also be important for the earliest stages of skeletal muscle growth and/or differentiation. It also plays a potential role in G2/M cell cycle regulation. It inhibits CREB activity by phosphorylating and repressing the CREB-specific coactivators, CRTC1-3.
Uniprot IDP57059
Protein Accession #NP_775490
Nucleotide Accession #NM_173354
Protein Size (# AA)783
Molecular Weight85 kDa
Protein InteractionsTAB2; MAP3K7; HDAC5; UBC; SUPT5H; RPL3; PRKACA; NMNAT1; STK11; ELAVL1; YWHAZ; PRKAA1; CRTC2; VAPA;
  1. What is the species homology for "SNF1LK Antibody - N-terminal region (ARP45918_T100)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit".

  2. How long will it take to receive "SNF1LK Antibody - N-terminal region (ARP45918_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "SNF1LK Antibody - N-terminal region (ARP45918_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "SNF1LK Antibody - N-terminal region (ARP45918_T100)"?

    This target may also be called "MSK, SIK, DEE30, SIK-1, SIK1B, SNF1LK" in publications.

  5. What is the shipping cost for "SNF1LK Antibody - N-terminal region (ARP45918_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "SNF1LK Antibody - N-terminal region (ARP45918_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "SNF1LK Antibody - N-terminal region (ARP45918_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "85 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "SNF1LK Antibody - N-terminal region (ARP45918_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "SIK1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "SIK1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "SIK1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "SIK1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "SIK1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "SIK1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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