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Catalog No: ARP34110_P050
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ARP34110_P050
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Datasheets/ManualsPrintable datasheet for anti-PTGER3 (ARP34110_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Horse, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human PTGER3
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceHorse: 100%; Human: 100%; Rabbit: 100%
Peptide SequenceSynthetic peptide located within the following region: ILDPWVYLLLRKILLRKFCQIRYHTNNYASSSTSLPCQCSSTLMWSDHLE
Concentration0.5 mg/ml
Blocking PeptideFor anti-PTGER3 (ARP34110_P050) antibody is Catalog # AAP34110 (Previous Catalog # AAPP05319)
ReferencePatwardhan,A.M., (2008) J. Dent. Res. 87 (3), 262-266
Gene SymbolPTGER3
Gene Full NameProstaglandin E receptor 3 (subtype EP3)
Alias SymbolsEP3, EP3e, EP3-I, EP3-II, EP3-IV, EP3-VI, PGE2-R, EP3-III, lnc003875
NCBI Gene Id5733
Protein NameProstaglandin E2 receptor EP3 subtype
Description of TargetPTGER3 is the receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems.The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple alternatively spliced transcript variants encoding eight distinct isoforms have been reported.
Uniprot IDP43115
Protein Accession #NP_942012
Nucleotide Accession #NM_198719
Protein Size (# AA)390
Molecular Weight43kDa
Protein InteractionsNOTCH2NL; INCA1; KRTAP10-3; KRTAP10-8; KRTAP10-9; KRTAP10-7; TRIM42; MGAT5B; KRT40; CCDC33; ADAMTSL4; EFEMP2; RGS17; SPRY2; KRT38; RGS20; TCF4; REL; MEOX2; KRT31; CDA; GHRL; MKLN1; PTGER1;
  1. What is the species homology for "PTGER3 Antibody - middle region (ARP34110_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Horse, Rabbit".

  2. How long will it take to receive "PTGER3 Antibody - middle region (ARP34110_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "PTGER3 Antibody - middle region (ARP34110_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PTGER3 Antibody - middle region (ARP34110_P050)"?

    This target may also be called "EP3, EP3e, EP3-I, EP3-II, EP3-IV, EP3-VI, PGE2-R, EP3-III, lnc003875" in publications.

  5. What is the shipping cost for "PTGER3 Antibody - middle region (ARP34110_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PTGER3 Antibody - middle region (ARP34110_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PTGER3 Antibody - middle region (ARP34110_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "43kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PTGER3 Antibody - middle region (ARP34110_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PTGER3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PTGER3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PTGER3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PTGER3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PTGER3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PTGER3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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