Catalog No: ARP33066_P050
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ARP33066_P050
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Datasheets/ManualsPrintable datasheet for anti-PPARA (ARP33066_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the n terminal region of human PPARA
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 93%; Goat: 93%; Guinea Pig: 92%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: EISQSIGEDSSGSFGFTEYQYLGSCPGSDGSVITDTLSPASSPSSVTYPV
Concentration0.5 mg/ml
Blocking PeptideFor anti-PPARA (ARP33066_P050) antibody is Catalog # AAP33066 (Previous Catalog # AAPP23992)
ReferenceKourimate,S., (2008) J. Biol. Chem. 283 (15), 9666-9673
Gene SymbolPPARA
Gene Full NamePeroxisome proliferator-activated receptor alpha
Alias SymbolsPPAR, NR1C1, hPPAR, PPARalpha, PPAR-alpha
NCBI Gene Id5465
Protein NamePeroxisome proliferator-activated receptor alpha
Description of TargetPeroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. PPARA is the subtype PPAR-alpha, which is a nuclear transcription factor.Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.
Uniprot IDQ07869
Protein Accession #NP_005027
Nucleotide Accession #NM_005036
Protein Size (# AA)468
Molecular Weight52kDa
Protein InteractionsSIRT1; PRMT1; PRMT8; RXRA; CHD9; NCOA1; FOXA3; CDK3; TNP1; HSP90AA1; NCOR2; NCOR1; SUMO1; UBE2I; LPIN1; SRC; TRA; MECR; STAC3; HELZ2; NRBF2; AIP; NR1H3; MED24; GADD45G; GADD45B; AKAP13; PPARGC1A; MED1; EP300; NRIP1; DAP3; MAPK3; DUT; RXRG; PRKCD; PRKCA; M
  1. What is the species homology for "PPARA Antibody - N-terminal region (ARP33066_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit".

  2. How long will it take to receive "PPARA Antibody - N-terminal region (ARP33066_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "PPARA Antibody - N-terminal region (ARP33066_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PPARA Antibody - N-terminal region (ARP33066_P050)"?

    This target may also be called "PPAR, NR1C1, hPPAR, PPARalpha, PPAR-alpha" in publications.

  5. What is the shipping cost for "PPARA Antibody - N-terminal region (ARP33066_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PPARA Antibody - N-terminal region (ARP33066_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PPARA Antibody - N-terminal region (ARP33066_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "52kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PPARA Antibody - N-terminal region (ARP33066_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PPARA"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PPARA"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PPARA"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PPARA"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PPARA"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PPARA"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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