Catalog No: ARP45619_P050
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ARP45619_P050
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Datasheets/ManualsPrintable datasheet for anti-NR5A1 (ARP45619_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human NR5A1
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 79%; Dog: 86%; Guinea Pig: 91%; Horse: 86%; Human: 100%; Pig: 92%; Rabbit: 79%; Rat: 86%; Sheep: 79%
Peptide SequenceSynthetic peptide located within the following region: SLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRA
Concentration0.5 mg/ml
Blocking PeptideFor anti-NR5A1 (ARP45619_P050) antibody is Catalog # AAP45619 (Previous Catalog # AAPP11902)
ReferenceClark,H.F., Mol. Cell. Biochem. 307 (1-2), 65-71 (2008)
Gene SymbolNR5A1
Gene Full NameNuclear receptor subfamily 5, group A, member 1
Alias SymbolsELP, SF1, FTZ1, POF7, SF-1, AD4BP, FTZF1, SPGF8, SRXX4, SRXY3, hSF-1
NCBI Gene Id2516
Protein NameSteroidogenic factor 1
Description of TargetNR5A1 is an important regulator of steroidogeneisis which is present in human skin and its appendages. It plays a role in regulating p450scc expression with TReP-132 and CBP/p300. The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Uniprot IDQ13285
Protein Accession #NP_004950
Nucleotide Accession #NM_004959
Protein Size (# AA)461
Molecular Weight52kDa
Protein InteractionsNCK2; NR0B1; RAD54L2; THOC2; ALYREF; EIF4A3; DDX39B; UBC; BARD1; ELAVL1; TCF7L2; CTNNB1; CREBBP; CXXC1; PNRC2; SOX8; PIAS1; ZNF653; TRERF1; EDF1; GATA4; GTF2B; SOX2; SOX9; TBX19; NCOA1; NRIP1; PITX1; SMARCD3; PROX1; AR; SP1; NFYA; MAPK1; JUN; NFKB2;
  1. What is the species homology for "NR5A1 Antibody - middle region (ARP45619_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep".

  2. How long will it take to receive "NR5A1 Antibody - middle region (ARP45619_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "NR5A1 Antibody - middle region (ARP45619_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "NR5A1 Antibody - middle region (ARP45619_P050)"?

    This target may also be called "ELP, SF1, FTZ1, POF7, SF-1, AD4BP, FTZF1, SPGF8, SRXX4, SRXY3, hSF-1" in publications.

  5. What is the shipping cost for "NR5A1 Antibody - middle region (ARP45619_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "NR5A1 Antibody - middle region (ARP45619_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "NR5A1 Antibody - middle region (ARP45619_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "52kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "NR5A1 Antibody - middle region (ARP45619_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "NR5A1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "NR5A1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "NR5A1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "NR5A1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "NR5A1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "NR5A1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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