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Catalog No: ARP45597_T100
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ARP45597_T100
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Datasheets/ManualsPrintable datasheet for anti-NR0B1 (ARP45597_T100) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human NR0B1
PurificationProtein A purified
Predicted Homology Based on Immunogen SequenceHuman: 100%
Peptide SequenceSynthetic peptide located within the following region: TSSKQTHVAPAAPEARPGGAWWDRSYFAQRPGGKEALPGGRATALLYRCC
Concentration1.0 mg/ml
Blocking PeptideFor anti-NR0B1 (ARP45597_T100) antibody is Catalog # AAP45597 (Previous Catalog # AAPP11876)
ReferenceMantovani,G., (2005) Fertil. Steril. 84 (5), 1542-1544
Gene SymbolNR0B1
Gene Full NameNuclear receptor subfamily 0, group B, member 1
Alias SymbolsAHC, AHX, DSS, GTD, HHG, AHCH, DAX1, DAX-1, NROB1, SRXY2
NCBI Gene Id190
Protein NameNuclear receptor subfamily 0 group B member 1
Description of TargetNR0B1 is a protein that contains a DNA-binding domain. The protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in its gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.
Uniprot IDP51843
Protein Accession #NP_000466
Nucleotide Accession #NM_000475
Protein Size (# AA)470
Molecular Weight52kDa
Protein InteractionsNR5A1; ESRRG; RORA; RNF31; UBC; NR3C1; ESRRA; SNW1; PPARG; POU5F1; PGR; AR; COPS2; NRIP1; ESR2; SREBF1; ESR1;
  1. What is the species homology for "NR0B1 Antibody - N-terminal region (ARP45597_T100)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "NR0B1 Antibody - N-terminal region (ARP45597_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "NR0B1 Antibody - N-terminal region (ARP45597_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "NR0B1 Antibody - N-terminal region (ARP45597_T100)"?

    This target may also be called "AHC, AHX, DSS, GTD, HHG, AHCH, DAX1, DAX-1, NROB1, SRXY2" in publications.

  5. What is the shipping cost for "NR0B1 Antibody - N-terminal region (ARP45597_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "NR0B1 Antibody - N-terminal region (ARP45597_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "NR0B1 Antibody - N-terminal region (ARP45597_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "52kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "NR0B1 Antibody - N-terminal region (ARP45597_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "NR0B1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "NR0B1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "NR0B1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "NR0B1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "NR0B1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "NR0B1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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