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100 ul
$289.00
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HDAC2 antibody - C-terminal region (ARP32618_P050)

Receive a free positive control (AHL002) when you purchase this antibody. Use the promotion code 'freecontrol' when placing your order.
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Description of Target:
Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human.
Gene Symbol:
HDAC2
Official Gene Full Name:
Histone deacetylase 2
NCBI Gene Id:
3066
Alias Symbols:
HD2; RPD3; YAF1
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HDAC2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HDAC2.
Swissprot Id:
Q92769
Protein Accession #:
NP_001518
Nucleotide Accession #:
NM_001527
Host:
Rabbit
Clonality:
Polyclonal
Protein Name:
Histone deacetylase 2
Protein Size (# AA):
488
Molecular Weight:
55kDa
Application:
IHC, WB
Protein Interactions:
BRCA1; SUMO1; UBC; SMAD7; SMAD2; MXD1; NCOR2; SUMO2; SFPQ; KDM5A; HDAC1; DDB1; CUL4B; CHFR; KDM1A; KDM5B; NFE2L2; PRDM6; DNMT3B; DNMT1; NACC2; HIST1H4A; HIST1H3A; HIST2H2BE; HIST2H2AC; PRDM1; EED; RNF2; SP1; CHD4; CHD3; ACTL6A; C16orf87; HMG20A; HMG20B; C
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human HDAC2
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Purification:
Affinity Purified
Complete computational species homology data:
Anti-HDAC2 (ARP32618_P050)
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 91%
Species Reactivity:
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Pig; Rabbit; Rat; Yeast
Datasheets / Downloads:
Printable datasheet for anti-HDAC2 (ARP32618_P050) antibody
Peptide Sequence:
Synthetic peptide located within the following region: EEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSK
Blocking Peptide:
For anti-HDAC2 (ARP32618_P050) antibody is Catalog # AAP32618 (Previous Catalog # AAPP03627)
Target Reference:
Choi, Y.B., et al., (2004) J.Biol.Chem.279(49),50930-50941
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Product Protocols: HDAC2 antibody tested with Human Jurkat Cells (ARP32618_P050)

Aviva Systems Biology is the original manufacturer of this HDAC2 antibody (ARP32618_P050)

Click here to view the HDAC2 antibody Western Blot Protocol

Product Datasheet Link: HDAC2 antibody (ARP32618_P050)

WB Suggested Anti-HDAC2 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat

Western Blot image:


Description of Target: Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human.

Questions pertaining to this data can be directed to techsupport@avivasysbio.com

Aviva Systems Biology’s HDAC2 antibody (ARP32618_P050) has been tested using other cell lysates and tissues. To obtain more data about this antibody please email us at info@avivasysbio.com.

To order by phone call us at (888) 880-0001, fax us at (858) 552-6975 or send an email to info@avivasysbio.com. Aviva manufactures this antibody so we can offer the best price. Please contact us to request pricing information.

All of Aviva’s products are guaranteed for the applications and experimental sample types mentioned in the datasheet below. Are you curious if this product will work for you? Please contact us at techsupport@avivasysbio.com

Product Protocols: HDAC2 antibody tested by IHC with human spermatophore (ARP32618)

Aviva Systems Biology is the original manufacturer of this HDAC2 antibody.

Click here to view the HDAC2 antibody Immunohistochemistry (IHC) protocol

Product Datasheet Link: HDAC2 antibody (ARP32618)

IHC Information:

Rabbit Anti-HDAC2 Antibody
Catalog Number: ARP32618
Paraffin Embedded Tissue: Human Spermatophore
Cellular Data: Epithelial cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X

IHC Image:

 
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