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HDAC2 antibody - C-terminal region (ARP32618_P050)

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Description of Target:
Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human.
Gene Symbol:
HDAC2
Official Gene Full Name:
Histone deacetylase 2
NCBI Gene Id:
3066
Alias Symbols:
HD2; RPD3; YAF1
Tissue Tool:
Find tissues and cell lines supported to express HDAC2.
Protein Accession #:
NP_001518
Nucleotide Accession#:
NM_001527
Swissprot Id:
Q92769
Host:
Rabbit
Clonality:
Polyclonal
Protein Name:
Histone deacetylase 2
Protein Size (# AA):
488
Molecular Weight:
55kDa
Application:
IHC, WB
Partner Proteins:
SMURF1, TBP, ASH2L, DNMT1, HIST2H3C, HIST2H4A, KIFC1, MEN1, MLL, MLL2, RBBP5, SETD1A, SETD1B, WDR5, WDR77, WDR82, WDR82P1
Immunogen:
The immunogen for anti-HDAC2 antibody: synthetic peptide directed towards the C terminal of human HDAC2
Product Format:
Lyophilized powder
Purification:
Affinity Purified
Complete computational species homology data:
HDAC2 antibody - C-terminal region (ARP32618_P050)
Predicted Homology Based on Immunogen Sequence:
Dog: 100%; Pig: 100%; Rat: 100%; Human: 100%; Mouse: 100%; Bovine: 100%; Rabbit: 100%; Horse: 93%; Guinea pig: 93%; Yeast: 91%
Species Reactivity:
Human, Bovine, Dog, Pig, Rabbit, Rat, Mouse, Horse, Guinea pig, Yeast
Datasheets / Downloads:
Printable datasheet for
anti-HDAC2 antibody
- ARP32618_P050
Peptide Sequence:
Synthetic peptide located within the following region: EEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSK
Blocking Peptide:
For anti-HDAC2 antibody is Catalog # AAP32618 (Previous Catalog # AAPP03627)
Key Reference:
Choi, Y.B., et al., (2004) J.Biol.Chem.279(49),50930-50941
Reconstitution and Storage:
Add 50 ul of distilled water. Final anti-HDAC2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
 
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