website statistics
Account Login 

Now Offering Over 102,157 Antibodies & 44,722 Antigens!

HDAC2 antibody - C-terminal region (ARP32618_P050)

  • Catalog#: ARP32618_P050
  • Domestic: within 1-2 days delivery International: 1-2 days
    *** Required Wet/Dry Ice Surcharge will automatically be applied upon checkout for the shipment. See Surcharges
    - Trial Size Available. Trial size is not available for conjugation.
Scroll Horizontally to view all Images
Print Page
100 ul
    $289.00
    In Stock

    Conjugation Options

    ARP32618_P050-FITC Conjugated

    ARP32618_P050-HRP Conjugated

    ARP32618_P050-Biotin Conjugated

    Gene Symbol:
    HDAC2
    NCBI Gene Id:
    3066
    Official Gene Full Name:
    Histone deacetylase 2
    Protein Name:
    Histone deacetylase 2
    Swissprot Id:
    Q92769
    Protein Accession #:
    NP_001518
    Nucleotide Accession #:
    NM_001527
    Alias Symbols:
    HD2, RPD3, YAF1
    Replacement Item:
    This antibody may replace item sc-44262 from Santa Cruz Biotechnology.
    Description of Target:
    Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human.
    Protein Size (# AA):
    488
    Molecular Weight:
    55kDa
    Host:
    Rabbit
    Clonality:
    Polyclonal
    Purification:
    Affinity Purified
    Application:
    IHC, WB
    Tissue Tool:
    Find tissues and cell lines supported by DNA array analysis to express HDAC2.
    RNA Seq:
    Find tissues and cell lines supported by RNA-seq analysis to express HDAC2.
    Immunogen:
    The immunogen is a synthetic peptide directed towards the C terminal region of human HDAC2
    Species Reactivity:
    Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Yeast
    Predicted Homology Based on Immunogen Sequence:
    Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 91%
    Complete computational species homology data:
    Anti-HDAC2 (ARP32618_P050)
    Peptide Sequence:
    Synthetic peptide located within the following region: EEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSK
    Product Format:
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
    Reconstitution and Storage:
    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
    Concentration:
    Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
    Protein Interactions:
    BRCA1; SUMO1; UBC; SMAD7; SMAD2; MXD1; NCOR2; SUMO2; SFPQ; KDM5A; HDAC1; DDB1; CUL4B; CHFR; KDM1A; KDM5B; NFE2L2; PRDM6; DNMT3B; DNMT1; NACC2; HIST1H4A; HIST1H3A; HIST2H2BE; HIST2H2AC; PRDM1; EED; RNF2; SP1; CHD4; CHD3; ACTL6A; C16orf87; HMG20A; HMG20B; C
    Blocking Peptide:
    For anti-HDAC2 (ARP32618_P050) antibody is Catalog # AAP32618 (Previous Catalog # AAPP03627)
    Datasheets / Downloads:
    Printable datasheet for anti-HDAC2 (ARP32618_P050) antibody
    Target Reference:
    Choi, Y.B., et al., (2004) J.Biol.Chem.279(49),50930-50941

    Product Protocols: HDAC2 antibody tested with Human Jurkat Cells (ARP32618_P050)

    Aviva Systems Biology is the original manufacturer of this HDAC2 antibody (ARP32618_P050)

    Click here to view the HDAC2 antibody Western Blot Protocol

    Product Datasheet Link: HDAC2 antibody (ARP32618_P050)

    WB Suggested Anti-HDAC2 Antibody Titration: 0.2-1 ug/ml
    Positive Control: Jurkat

    Western Blot image:


    Description of Target: Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human.

    Questions pertaining to this data can be directed to techsupport@avivasysbio.com

    Aviva Systems Biology’s HDAC2 antibody (ARP32618_P050) has been tested using other cell lysates and tissues. To obtain more data about this antibody please email us at info@avivasysbio.com.

    To order by phone call us at (888) 880-0001, fax us at (858) 552-6975 or send an email to info@avivasysbio.com. Aviva manufactures this antibody so we can offer the best price. Please contact us to request pricing information.

    All of Aviva’s products are guaranteed for the applications and experimental sample types mentioned in the datasheet below. Are you curious if this product will work for you? Please contact us at techsupport@avivasysbio.com

    Product Protocols: HDAC2 antibody tested by IHC with human spermatophore (ARP32618)

    Aviva Systems Biology is the original manufacturer of this HDAC2 antibody.

    Click here to view the HDAC2 antibody Immunohistochemistry (IHC) protocol

    Product Datasheet Link: HDAC2 antibody (ARP32618)

    IHC Information:

    Rabbit Anti-HDAC2 Antibody
    Catalog Number: ARP32618
    Paraffin Embedded Tissue: Human Spermatophore
    Cellular Data: Epithelial cells
    Antibody Concentration: 4.0-8.0 ug/ml
    Magnification: 400X

    IHC Image:

     
    X
    Ask a Question