CRK Protein Lysate (GST tagged) (Expressed in bacteria) (200ug)

Catalog#: APL10439

• Size: 200ug

• Description of Target: This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
• Gene Symbol: CRK
• Alias Symbols: CRKII; p38
• Protein Accession#: NP_005197
• Nucleotide Accession#: NM_005206
• Swissprot Id: P46108
• Molecular Weight: 38
• Tag: GST in N-terminal
• Quality Control: This product was tested on western blot.
  Application : Western blot standard.
  Observed Molecular Weight: 38
  Expression system : Bacteria
• Reconstitution and Storage: Add 200ul of distilled water. Final concentration is 1 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
• Additional Information: Buffer Formulation: 0.1M Tris-HCl (pH 6.8) buffer containing 0.2M DTT, 4% SDS, 0.2% Bromophenol blue and 20% Sucrose.
• Key Reference: N/A