Catalog No: ARP30622_P050
Price: $0.00
SKU
ARP30622_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for anti-TNFRSF10A (ARP30622_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceHuman: 100%; Mouse: 80%
Peptide SequenceSynthetic peptide located within the following region: RAGTAGPGDALYAMLMKWVNKTGRNASIHTLLDALERMEERHAKEKIQDL
Concentration0.5 mg/ml
Blocking PeptideFor anti-TNFRSF10A (ARP30622_P050) antibody is Catalog # AAP30622
Gene SymbolTNFRSF10A
Gene Full NameTumor necrosis factor receptor superfamily, member 10a
Alias SymbolsDR4, APO2, CD261, TRAILR1, TRAILR-1
NCBI Gene Id8797
Protein NameTumor necrosis factor receptor superfamily member 10A
Description of TargetThis is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adaptor molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
Uniprot IDO00220
Protein Accession #NP_003835
Nucleotide Accession #NM_003844
Protein Size (# AA)468
Molecular Weight50kDa
Protein InteractionsUBC; MARCH8; MARCH1; CFLAR; FADD; CUL3; TRAF2; CASP8; SQSTM1; TNFRSF10B; CBL; MOAP1; RASSF1; TNFRSF10D; TNFRSF10A; TNFSF10; MADD; BCL10; TRADD; RIPK1; DAP3; BTK; CD4; COL2A1; CASP10;
  1. What is the species homology for "TNFRSF10A Antibody - C-terminal region (ARP30622_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse".

  2. How long will it take to receive "TNFRSF10A Antibody - C-terminal region (ARP30622_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "TNFRSF10A Antibody - C-terminal region (ARP30622_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "TNFRSF10A Antibody - C-terminal region (ARP30622_P050)"?

    This target may also be called "DR4, APO2, CD261, TRAILR1, TRAILR-1" in publications.

  5. What is the shipping cost for "TNFRSF10A Antibody - C-terminal region (ARP30622_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "TNFRSF10A Antibody - C-terminal region (ARP30622_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "TNFRSF10A Antibody - C-terminal region (ARP30622_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "50kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "TNFRSF10A Antibody - C-terminal region (ARP30622_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "TNFRSF10A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "TNFRSF10A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "TNFRSF10A"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "TNFRSF10A"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "TNFRSF10A"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "TNFRSF10A"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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