MRPS16 Antibody - C-terminal region (ARP66866_P050)

Catalog No: ARP66866_P050

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Host: Rabbit
Target Name: MRPS16
Sample Type: 293T Whole Cell lysates
Antibody Dilution: 1.0ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Rat, Guinea Pig
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MRPS16
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Guinea Pig: 75%; Human: 100%; Rat: 75%
• Peptide Sequence: Synthetic peptide located within the following region: EKLLGLAGFFPLHPMMITNAERLRRKRAREVLLASQKTDAEATDTEATET
• Concentration: 0.5 mg/ml
• Blocking Peptide: Catalog # AAP66866

Target Info

• Gene Symbol: MRPS16
• Alias Symbols: COXPD2, RPMS16, CGI-132, MRP-S16
• NCBI Gene Id: 51021
• Protein Name: 28S ribosomal protein S16, mitochondrial
• Description of Target: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S16P family. The encoded protein is one of the most highly conserved ribosomal proteins between mammalian and yeast mitochondria. Three pseudogenes (located at 8q21.3, 20q13.32, 22q12-q13.1) for this gene have been described.
• Uniprot ID: Q9Y3D3
• Protein Accession #: NP_057149
• Nucleotide Accession #: NM_016065
• Protein Size (# AA): 137
• Molecular Weight: 15kDa
• Protein Interactions: CEP76; UBC; HNRNPU; MRPS9; MRPS26; MRPS25; MRPS2; MCAT; FAM50B; HNRNPR; HNRNPDL; SSBP1; PSMC2; PSMC1; PSMA7; PSMA5; MPV17; SLC25A5; ATXN10; CAND1; ZP3; ELAVL1; ICT1;