PTPRN Antibody - middle region (ARP45381_P050)

Catalog No: ARP45381_P050

Host: Rabbit
Target Name: PTPRN
Sample Type: Human Kidney
Antibody Dilution: 0.5 ug/ml

Host: Rabbit
Target Name: PTPRN
Sample Tissue: Human Liver Tumor
Antibody Dilution: 1ug/ml

Host: Rabbit
Target Name: PTPRN
Sample Tissue: Human A172 Whole Cell
Antibody Dilution: 5ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PTPRN
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 86%; Dog: 100%; Guinea Pig: 85%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 86%; Rabbit: 100%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: EVQQVPSPVSSEPPKAARPPVTPVLLEKKSPLGQSQPTVAGQPSARPAAE
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-PTPRN (ARP45381_P050) antibody is Catalog # AAP45381 (Previous Catalog # AAPP26354)

Target Info

• Gene Symbol: PTPRN
• Gene Full Name: Protein tyrosine phosphatase, receptor type, N
• Alias Symbols: IA2, IA-2, ICA512, R-PTP-N, IA-2/PTP
• NCBI Gene Id: 5798
• Protein Name: Protein tyrosine phosphatase, receptor type, N EMBL AAP35621.1
• Description of Target: PTPRN is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.
• Uniprot ID: Q16849
• Protein Accession #: EAW70725
• Nucleotide Accession #: NM_001199763
• Protein Size (# AA): 889
• Molecular Weight: 96kDa
• Protein Interactions: PLP1; MAL; CLN8; UBQLN4; SNX19; SPTBN4; PTPRT; MADD; PTPRS; SNTB2; NOS1; PPIA; CAPN2;