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- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid PBS with 0.09% sodium azide |
| Clonality | Monoclonal |
| Clone | 5B8 |
| Isotype | IgG1 |
| Host | Mouse |
| Additional Information | Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of the X63-Ag8-653 myeloma cell line. |
| Reconstitution and Storage | Store at 4C or at -20C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch. |
| Immunogen | Recombinant human proinsulin |
| Purification | Affinity chromatography on Protein A from tissue culture supernatant. |
| Concentration | 1 mg/ml |
| Specificity | Mouse anti Human C-Peptide antibody, clone 5B8 recognizes human C-peptide. This product does not cross-react with human, bovine, porcine, mouse or rat insulin. |
| Warning | This product contains sodium azide, which forms hydrazoic acid under acidic conditions and may react with lead or copper plumbing to produce explosive metal azides. On disposal, flush with large amounts of water to prevent accumulation. |
| Gene Symbol | INS |
|---|---|
| Alias Symbols | IDDM, ILPR, IRDN, IDDM1, IDDM2, PNDM4, MODY10 |
| NCBI Gene Id | 3630 |
| Protein Name | Insulin |
| Description of Target | C-peptide is a 31 amino acid peptide released when proinsulin is split into insulin and C-peptide. Proinsulin is split when it is released from the pancreas into the blood in response to a rise in serum glucose levels. C-peptide function is not fully understood, it binds to cell membranes which leads to increased intracellular Ca2+ concentration and subsequent stimulation of N+, K+-ATPase and endothelial nitric oxide synthase activities. C-peptide also functions in repair of the muscular layer of arteries. Levels of C-peptide can be used to distinguish between type 1 and type 2 diabetes. Patients with type 1 diabetes usually have decreased levels of C-peptide, while patients with type 2 diabetes will have normal or higher than normal levels. |
| Uniprot ID | P01308 |
| Protein Accession # | NP_000198.1 |
| Protein Size (# AA) | 110 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "INS Antibody (OASA02647)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "INS Antibody (OASA02647)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "INS Antibody (OASA02647)" provided in?
This item is provided in "Liquid PBS with 0.09% sodium azide".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "INS Antibody (OASA02647)"?
This target may also be called "IDDM, ILPR, IRDN, IDDM1, IDDM2, PNDM4, MODY10" in publications.
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What is the shipping cost for "INS Antibody (OASA02647)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "INS Antibody (OASA02647)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "INS Antibody (OASA02647)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "INS Antibody (OASA02647)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "INS"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "INS"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "INS"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "INS"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "INS"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "INS"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
