PCYOX1 antibody - C-terminal region (ARP33007_T100)

Catalog#: ARP33007_T100

• Size: 100ug

Human Jurkat

Human Liver

• Description of Target: Prenylated proteins contain one of two isoprenoid lipids, either the 15-carbon farnesyl or the 20-carbon geranylgeranyl, covalently attached to cysteine residues at or near their C terminus. PCYOX1 is capable of cleaving the thioether bond of prenylcysteines. The enzyme was isolated from bovine brain membranes and exhibits an apparent molecular mass of 63 kDa. This is a specific enzyme involved in prenylcysteine metabolism in mammalian cells, most likely comprising the final step in the degradation of prenylated proteins.
• Gene Symbol: PCYOX1
• Official Gene Full Name: Prenylcysteine oxidase 1
• Alias Symbols: PCL1
• Protein Accession#: NP_057381
• Nucleotide Accession#: NM_016297
• Swissprot Id: Q9UHG3
• Host: Rabbit
• Clonality: Polyclonal
• Protein Size (# AA): 505
• Molecular Weight: 57kDa
• Application: WB, IHC
• Partner Proteins: ETS1, ETS1, ETS2, FLI1, HTNVsSgp1, SUMO1, UBE2I, CD40, ETS1, ETS2, FLI1, SKIL, SUMO1, TNFRSF1B, TNFRSF8, TRAF2, TRAF3, TRAF5, TRAF6, UBE2I, CD40, ETS1, SUMO1, TNFRSF1B, TNFRSF8, TRAF2, TRAF3, TRAF5, TRAF6, UBE2I
• Immunogen: The immunogen for anti-PCYOX1 antibody: synthetic peptide directed towards the C terminal of human PCYOX1
• Product Format: Lyophilized powder
• Purification: Protein A purified
• Predicted Homology Based on Immunogen Sequence: Human: 100%; Rabbit: 100%; Dog: 85%; Horse: 85%
• Peptide Sequence: Synthetic peptide located within the following region: IFSQETLTKAQILKLFLSYDYAVKKPWLAYPHYKPPEKCPSIILHDRLYY
• Blocking Peptide: For anti-PCYOX1 antibody is Catalog # AAP33007 (Previous Catalog # AAPP04036)
• Key Reference: Clark,H.F., et al., (2003) Genome Res. 13 (10), 2265-2270
• Reconstitution and Storage: Add 100 μl of distilled water. Final anti-PCYOX1 antibody concentration is 1 mg/ml in PBS buffer. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.

Product Protocols: PCYOX1 antibody tested with Human Jurkat Cells (ARP33007_T100)

Aviva Systems Biology is the original manufacturer of this PCYOX1 antibody (ARP33007_T100)

Click here to view the PCYOX1 antibody Western Blot Protocol

Product Datasheet Link: PCYOX1 antibody (ARP33007_T100)

WB Suggested Anti-PCYOX1 Antibody Titration: 0.5ug/ml
Positive Control: Jurkat

Western Blot image:


Description of Target: Prenylated proteins contain one of two isoprenoid lipids, either the 15-carbon farnesyl or the 20-carbon geranylgeranyl, covalently attached to cysteine residues at or near their C terminus. PCYOX1 is capable of cleaving the thioether bond of prenylcysteines. The enzyme was isolated from bovine brain membranes and exhibits an apparent molecular mass of 63 kDa. This is a specific enzyme involved in prenylcysteine metabolism in mammalian cells, most likely comprising the final step in the degradation of prenylated proteins.

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Aviva Systems Biology’s PCYOX1 antibody (ARP33007_T100) has been tested using other cell lysates and tissues. To obtain more data about this antibody please email us at info@avivasysbio.com.

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Product Protocols: PCYOX1 antibody tested by IHC with human liver (ARP33007)

Aviva Systems Biology is the original manufacturer of this PCYOX1 antibody.

Click here to view the PCYOX1 antibody Immunohistochemistry (IHC) protocol

Product Datasheet Link: PCYOX1 antibody (ARP33007)

IHC Information:

Rabbit Anti-PCYOX1 Antibody
Catalog Number: ARP33007
Paraffin Embedded Tissue: Human Liver
Cellular Data: Liver cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X

IHC Image: