- Description of Target:
- HCLS1 Tyr phosphorylation catalyzed by Syk and Lyn plays a crucial role in the translocation of the protein to the membrane and is involved in the cytoskeleton rearrangement triggered by thrombin in human platelets. This gene is a substrate for caspase cleavage during apoptosis.
- Gene Symbol:
- HCLS1
- Official Gene Full Name:
- Hematopoietic cell-specific Lyn substrate 1
- Alias Symbols:
- HS1; CTTNL
- Tissue Tool:
- Find tissues and cell lines supported to express HCLS1.

- Protein Accession# :
- NP_005326
- Nucleotide Accession#:
- NM_005335
- Swissprot Id:
- P14317
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Protein Size (# AA):
- 486
- Molecular Weight:
- 54kDa
- Application:
- WB, IHC
- Partner Proteins:
- BRCA1, DNMT1, DNMT3B, PA2G4, SIN3A, SMARCA5, STAT3, TNFSF10, YY1, ANTXR1, ARID4A, BRCA1, BRMS1, BRMS1L, BUB3, CDC20, CDH1, CDYL, CIR1, CSNK2A1, CSNK2A2, CTBP1, DAXX, DDX20, DMAP1, DNMT1, DNMT3B, EED, EID2, FKBP3, HDAC1, HDAC10, HIF1AN, HOPX, IFRD1, IKZF1, IKZF4, ING1, MAD1L1, MBD2, MTA1, MXD1, NR
- Immunogen:
- The immunogen for anti-HCLS1 antibody: synthetic peptide directed towards the N terminal of human HCLS1
- Product Format:
- Lyophilized powder
- Purification:
- Protein A purified
- Complete computational species homology data:
- HCLS1 antibody - N-terminal region (ARP31928_T100)
- Predicted Homology Based on Immunogen Sequence:
- Human: 100%; Bovine: 85%; Dog: 85%; Guinea pig: 85%; Horse: 85%; Mouse: 85%; Pig: 85%; Rabbit: 85%; Rat: 84%
- Datasheets / Downloads:
- Printable datasheet for
anti-HCLS1 antibody
- ARP31928_T100 - Peptide Sequence:
- Synthetic peptide located within the following region: VNDISEKEQRWGAKTIEGSGRTEHINIHQLRNKVSEEHDVLRKKEMESGP
- Blocking Peptide:
- For anti-HCLS1 antibody is Catalog # AAP31928
- Key Reference:
- Ruzzene,M., et al., (2002) Biochem. J. 364 (Pt 1), 41-47
- Reconstitution and Storage:
- Add 100 μl of distilled water. Final anti-HCLS1 antibody concentration is 1 mg/ml in PBS buffer. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Product Protocols: HCLS1 antibody tested by IHC with human stomach (ARP31928)
Aviva Systems Biology is the original manufacturer of this HCLS1 antibody.
Click here to view the HCLS1 antibody Immunohistochemistry (IHC) protocol
Product Datasheet Link: HCLS1 antibody (ARP31928)
IHC Information:
Rabbit Anti-HCLS1 Antibody
Catalog Number: ARP31928
Paraffin Embedded Tissue: Human Stomach
Cellular Data: Epithelial cells of Fundic Gland
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
IHC Image:
Product Protocols: HCLS1 antibody tested by IHC with human kidney (ARP31928)
Aviva Systems Biology is the original manufacturer of this HCLS1 antibody.
Click here to view the HCLS1 antibody Immunohistochemistry (IHC) protocol
Product Datasheet Link: HCLS1 antibody (ARP31928)
IHC Information:
Rabbit Anti-HCLS1 Antibody
Catalog Number: ARP31928
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
IHC Image:
Product Protocols: HCLS1 antibody tested by IHC with human heart (ARP31928)
Aviva Systems Biology is the original manufacturer of this HCLS1 antibody.
Click here to view the HCLS1 antibody Immunohistochemistry (IHC) protocol
Product Datasheet Link: HCLS1 antibody (ARP31928)
IHC Information:
Rabbit Anti-HCLS1 Antibody
Catalog Number: ARP31928
Paraffin Embedded Tissue: Human Heart
Cellular Data: Myocardial cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
IHC Image:
- Protocol:
- Tips Information:
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