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Catalog No: AVARP01018_P050
Price: $0.00
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AVARP01018_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for anti-FOXO4 (AVARP01018_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Dog, Horse, Pig
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human FOXO4
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceDog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: YLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPI
Concentration0.5 mg/ml
Blocking PeptideFor anti-FOXO4 (AVARP01018_P050) antibody is Catalog # AAP30320 (Previous Catalog # AAPP00701)
ReferenceBoura,E., (2007) J. Biol. Chem. 282 (11), 8265-8275
Gene SymbolFOXO4
Gene Full NameForkhead box O4
Alias SymbolsAFX, AFX1, MLLT7
NCBI Gene Id4303
Protein NameForkhead box protein O4
Description of TargetFOXO4 is transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. The protein can down-regulate expression of HIF1A and suppress hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias.
Uniprot IDP98177
Protein Accession #NP_005929
Nucleotide Accession #NM_005938
Protein Size (# AA)505
Molecular Weight54kDa
Protein InteractionsREL; SFN; AKT1; OGT; UBC; ATXN3; MDM2; NLK; USP7; CTNNB1; CREBBP; VDR; SIRT1; SMAD3; XPO1; YWHAZ; SMAD4; FOXG1; AKT2; ESR1; PIN1; CCND1; CDKN1A;
  1. What is the species homology for "FOXO4 Antibody - middle region (AVARP01018_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Dog, Horse, Pig".

  2. How long will it take to receive "FOXO4 Antibody - middle region (AVARP01018_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "FOXO4 Antibody - middle region (AVARP01018_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "FOXO4 Antibody - middle region (AVARP01018_P050)"?

    This target may also be called "AFX, AFX1, MLLT7" in publications.

  5. What is the shipping cost for "FOXO4 Antibody - middle region (AVARP01018_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "FOXO4 Antibody - middle region (AVARP01018_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "FOXO4 Antibody - middle region (AVARP01018_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "54kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "FOXO4 Antibody - middle region (AVARP01018_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "FOXO4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "FOXO4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "FOXO4"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "FOXO4"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "FOXO4"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "FOXO4"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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