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Datasheets/Manuals | Printable datasheet for ARP60159_P050 |
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Tested Species Reactivity | Human |
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Predicted Species Reactivity | Human |
Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Clonality | Polyclonal |
Host | Rabbit |
Application | WB |
Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Immunogen | The immunogen is a synthetic peptide directed towards the N-terminal region of Human DAXX |
Purification | Affinity Purified |
Peptide Sequence | Synthetic peptide located within the following region: KLNLAPAATTSNEPSGNNPPTHLSLDPTNAENTASQSPRTRGSRRQIQRL |
Concentration | 0.5 mg/ml |
Blocking Peptide | Catalog # AAP60159 |
Gene Symbol | DAXX |
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Alias Symbols | DAP6, EAP1, BING2, SMIM40 |
NCBI Gene Id | 1616 |
Description of Target | This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. |
Uniprot ID | Q9UER7 |
Protein Accession # | NP_001341 |
Protein Size (# AA) | 740 |
Molecular Weight | 81kDa |
Protein Interactions | FAM9B; SSX2IP; SUMO1; UBE2I; UBC; GOLGA2; CARD9; PBXIP1; CDCA7L; NECAB2; RASSF1; PML; MDM2; H3F3A; DNMT1; TP53; ATRX; CARM1; PRMT1; WHSC1L1; CUL3; SPOP; HIPK2; PDCD4; DNMT3A; USP7; UBB; RELB; DAXX; CREB1; CBS; ATM; HIST1H4F; HIST1H3C; TRAF3; HIST4H4; BTBD |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "DAXX Antibody - N-terminal region (ARP60159_P050)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human".
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How long will it take to receive "DAXX Antibody - N-terminal region (ARP60159_P050)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
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What buffer format is "DAXX Antibody - N-terminal region (ARP60159_P050)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "DAXX Antibody - N-terminal region (ARP60159_P050)"?
This target may also be called "DAP6, EAP1, BING2, SMIM40" in publications.
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What is the shipping cost for "DAXX Antibody - N-terminal region (ARP60159_P050)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "DAXX Antibody - N-terminal region (ARP60159_P050)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "DAXX Antibody - N-terminal region (ARP60159_P050)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "81kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "DAXX Antibody - N-terminal region (ARP60159_P050)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "DAXX"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "DAXX"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "DAXX"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "DAXX"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "DAXX"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "DAXX"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.