ARPC1B Antibody - middle region (ARP65735_P050)

Catalog No: ARP65735_P050

WB Suggested Anti-ARPC1B Antibody
Titration: 1.0 ug/ml
Positive Control: Fetal Lung

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human ARPC1B
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
• Peptide Sequence: Synthetic peptide located within the following region: KKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVEERPAPTPWGS
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-ARPC1B (ARP65735_P050) antibody is Catalog # AAP65735
• Subunit: 1B

Target Info

• Gene Symbol: ARPC1B
• Gene Full Name: actin related protein 2/3 complex subunit 1B
• Alias Symbols: ARC41, IMD71, PLTEID, p40-ARC, p41-ARC
• NCBI Gene Id: 10095
• Protein Name: actin-related protein 2/3 complex subunit 1B
• Description of Target: This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.
• Uniprot ID: O15143
• Protein Accession #: NP_005711
• Nucleotide Accession #: NM_005720
• Protein Size (# AA): 372
• Molecular Weight: 41kDa
• Protein Interactions: SUMO2; UBC; SUMO1; NEDD8; BTF3L4; C14orf142; IPO11; TPRKB; PDCD4; ANP32B; ARPC2; ACTR2; ACTR3; ARPC3; ARPC4; ARPC5; TOM1L1; ANP32A; VBP1; UBE3A; TPD52L2; TPD52; RPA2; RANGAP1; PRKACB; PPP2R5D; METTL1; HSF1; DR1; DHPS; CALU; CALR; AARS; SRPK2; PAN2; WASL;