TERF2 antibody - C-terminal region (ARP30228_T100)

Catalog#: ARP30228_T100

• Size: 100ug

Transfected 293T

• Description of Target: TERF2 is a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Gene Symbol: TERF2
• Official Gene Full Name: Telomeric repeat binding factor 2
• Alias Symbols: TRBF2; TRF2
• Protein Accession#: NP_005643
• Nucleotide Accession#: NM_005652
• Swissprot Id: Q15554
• Host: Rabbit
• Clonality: Polyclonal
• Protein Size (# AA): 500
• Molecular Weight: 55kDa
• Application: WB
• Partner Proteins: ATM, ATM, AATF, ASF1A, ATM, ATM, ATR, BRCA1, CDC25A, CDC25C, DBF4, E2F1, ERCC6, KPNA2, MDC1, MDM2, MDM4, MRC1, MSH2, MUS81, NBN, PLK1, PLK3, PPP2R2A, PPP2R2B, PPP2R5A, PPP2R5B, PPP2R5C, PPP2R5D, PPP2R5E, RAD9A, TP53, TSSK1B, ATMIN, BRCA1, BRCA2, CDC25A, GINS2, MDC1, MDM2, MSH2, MUS81, PLK1, PLK3, R
• Immunogen: The immunogen for anti-TERF2 antibody: synthetic peptide directed towards the C terminal of human TERF2
• Product Format: Lyophilized powder
• Purification: Protein A purified
• Predicted Homology Based on Immunogen Sequence: African clawed frog: 100%; Bovine: 100%; Dog: 100%; Guinea pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: TVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRLGMN
• Blocking Peptide: For anti-TERF2 antibody is Catalog # AAP30228 (Previous Catalog # AAPS09106)
• Key Reference: Etheridge,K.T., (2008) J. Biol. Chem. 283 (11), 6935-6941
• Reconstitution and Storage: Add 100 μl of distilled water. Final anti-TERF2 antibody concentration is 1 mg/ml in PBS buffer. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.

Product Protocols: TERF2 antibody tested with Human Transfected 293T Cells (ARP30228_T100)

Aviva Systems Biology is the original manufacturer of this TERF2 antibody (ARP30228_T100)

Click here to view the TERF2 antibody Western Blot Protocol

Product Datasheet Link: TERF2 antibody (ARP30228_T100)

WB Suggested Anti-TERF2 Antibody Titration: 5.0ug/ml
ELISA Titer: 1:62500
Positive Control: Transfected 293T

Western Blot image:


Description of Target: TERF2 is a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

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Aviva Systems Biology’s TERF2 antibody (ARP30228_T100) has been tested using other cell lysates and tissues. To obtain more data about this antibody please email us at info@avivasysbio.com.

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