- Description of Target:
- The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
- Gene Symbol:
- Official Gene Full Name:
- Calcium channel, voltage-dependent, beta 3 subunit
- NCBI Gene Id:
- Alias Symbols:
- CAB3; CACNLB3
- Sample Type Confirmation:
CACNB3 is strongly supported by BioGPS gene expression data to be expressed in Jurkat
- Tissue Tool:
- Find tissues and cell lines supported by DNA array analysis to express CACNB3.
- RNA Seq:
- Find tissues and cell lines supported by RNA-seq analysis to express CACNB3.
- Swissprot Id:
- Protein Accession #:
- Nucleotide Accession #:
- Protein Name:
- Voltage-dependent L-type calcium channel subunit beta-3
- Protein Size (# AA):
- Molecular Weight:
- Protein Interactions:
- FASLG; CACNA1C;
- The immunogen is a synthetic peptide directed towards the n terminal region of human CACNB3
- Product Format:
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
- Affinity Purified
- Complete computational species homology data:
- Anti-CACNB3 (ARP34958_P050)
- Predicted Homology Based on Immunogen Sequence:
- Cow: 100%; Dog: 92%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
- Species Reactivity:
- Cow; Dog; Guinea Pig; Human; Mouse; Rabbit; Rat; Zebrafish
- Datasheets / Downloads:
- Printable datasheet for anti-CACNB3 (ARP34958_P050) antibody
- Peptide Sequence:
- Synthetic peptide located within the following region: MYDDSYVPGFEDSEAGSADSYTSRPSLDSDVSLEEDRESARREVESQAQQ
- Blocking Peptide:
- For anti-CACNB3 (ARP34958_P050) antibody is Catalog # AAP34958 (Previous Catalog # AAPP06181)
- Reconstitution and Storage:
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Aviva Systems Biology is the original manufacturer of this CACNB3 antibody (ARP34958_P050)
Click here to view the CACNB3 antibody Western Blot Protocol
Product Datasheet Link: CACNB3 antibody (ARP34958_P050)
WB Suggested Anti-CACNB3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat
Western Blot image:
Description of Target: The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
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