- Description of Target:
- This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.
- Gene Symbol:
- MAP3K14
- Official Gene Full Name:
- Mitogen-activated protein kinase kinase kinase 14
- Alias Symbols:
- FTDCR1B; HS; HSNIK; NIK
- Tissue Tool:
- Find tissues and cell lines supported to express MAP3K14.

- Protein Accession# :
- NP_003945
- Nucleotide Accession#:
- NM_003954
- Swissprot Id:
- Q99558
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Protein Size (# AA):
- 947
- Molecular Weight:
- 104kDa
- Application:
- WB
- Partner Proteins:
- CHUK, IKBKAP, IKBKB, TRAF1, TRAF2, TRAF3, TRAF5, TRAF6, ALPL, CASP8, CDC37, CHUK, EDAR, EGFR, FBL, GRB10, GRB14, GRB7, HSP90AA1, HSP90AB1, IKBKAP, IKBKB, IKBKG, MAP2K4, MAP3K14, MAP3K7, MAP3K8, MAPK3, NFKB2, PEBP1, PELI3, RIPK1, RPL30, RPL4, RPL5, RPL6, RPS11, RPS13, TRAF1, TRAF2, TRAF3, TRAF5, TRAF6, CASP10, CASP3, CASP8, CFLAR, CHUK, EGFR, IKBKAP, IKBKB, IKBKG, MAP3K14, MAP3K7, MAP3K8, NFKB2, NFKBIA, Pebp1, RIPK1, TRAF1, TRAF2, TRAF3, TRAF6, Traf6
- Immunogen:
- The immunogen for anti-MAP3K14 antibody: synthetic peptide directed towards the N terminal of human MAP3K14
- Product Format:
- Lyophilized powder
- Purification:
- Affinity Purified
- Complete computational species homology data:
- MAP3K14 antibody - N-terminal region (ARP42161_P050)
- Predicted Homology Based on Immunogen Sequence:
- Bovine: 100%; Dog: 100%; Horse: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Chicken: 92%
- Datasheets / Downloads:
- Printable datasheet for
anti-MAP3K14 antibody
- ARP42161_P050 - Peptide Sequence:
- Synthetic peptide located within the following region: SEAGPAAISIIAQAECENSQEFSPTFSERIFIAGSKQYSQSESLDQIPNN
- Blocking Peptide:
- For anti-MAP3K14 antibody is Catalog # AAP42161 (Previous Catalog # AAPS11910)
- Reconstitution and Storage:
- Add 50 μl of distilled water. Final anti-MAP3K14 antibody concentration is 1 mg/ml in PBS buffer. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Product Protocols: MAP3K14 antibody tested with Human Thp-1 Cells (ARP42161_P050)
Aviva Systems Biology is the original manufacturer of this MAP3K14 antibody (ARP42161_P050)
Click here to view the MAP3K14 antibody Western Blot Protocol
Product Datasheet Link: MAP3K14 antibody (ARP42161_P050)
WB Suggested Anti-MAP3K14 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: THP-1
Western Blot image: 
Description of Target: This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.
Questions pertaining to this data can be directed to techsupport@avivasysbio.com
Aviva Systems Biology’s MAP3K14 antibody (ARP42161_P050) has been tested using other cell lysates and tissues. To obtain more data about this antibody please email us at info@avivasysbio.com.
To order by phone call us at (888) 880-0001, fax us at (858) 552-6975 or send an email to info@avivasysbio.com. Aviva manufactures this antibody so we can offer the best price. Please contact us to request pricing information.
All of Aviva’s products are guaranteed for the applications and experimental sample types mentioned in the datasheet below. Are you curious if this product will work for you? Please contact us at techsupport@avivasysbio.com
- Protocol:
- Tips Information:
See our General FAQ page.


