Aviva Systems Biology will be closed in observance of Good Friday 3/29/2024. If you are in need of any assistance please email info@avivasysbio.com

Catalog No: AVARP09014_P050
Price: $0.00
SKU
AVARP09014_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
Bulk
Order
Aviva's
Satisfaction
Guarantee
Contact Us:
Shipping Info:
  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.
Datasheets/ManualsPrintable datasheet for anti-HSPD1 (AVARP09014_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Rat, Guinea Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C terminal region of human HSPD1
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceGuinea Pig: 90%; Human: 84%; Rabbit: 84%; Rat: 84%
Peptide SequenceSynthetic peptide located within the following region: PTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAMGGMGGGMGG
Concentration0.5 mg/ml
Blocking PeptideFor anti-HSPD1 (AVARP09014_P050) antibody is Catalog # AAP30181 (Previous Catalog # AAPS08909)
ReferenceHewamadduma,C.A., (2008) Neurology 70 (19), 1717-1718
Publications

Depletion of mitochondrial protease OMA1 alters proliferative properties and promotes metastatic growth of breast cancer cells. Sci Rep. 9, 14746 (2019). 31611601

Description
Gene SymbolHSPD1
Gene Full NameHeat shock 60kDa protein 1 (chaperonin)
Alias SymbolsHLD4, CPN60, GROEL, HSP60, HSP65, SPG13, HSP-60, HuCHA60
NCBI Gene Id3329
Protein Name60 kDa heat shock protein, mitochondrial
Description of TargetHSPD1 is a member of the chaperonin family. This mitochondrial protein may function as a signaling molecule in the innate immune system. It is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Two pseudogenes, both located on chromosome 8, have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
Uniprot IDP10809
Protein Accession #NP_002147
Nucleotide Accession #NM_002156
Protein Size (# AA)573
Molecular Weight61kDa
Protein InteractionsRGS20; NOTCH2NL; KRTAP10-3; KRTAP10-8; SAMD3; KRT40; LZTS2; CEP70; HUWE1; TMCC2; KRT31; KRTAP5-9; FUS; TUBGCP3; AURKB; VCP; UBC; TUBG1; AURKA; SUMO3; LGALS3BP; CDC20; STAU1; LGR4; NEDD8; MDM2; ERG; ASB4; EED; MAPK14; ATP6V1A; RAB1B; C12orf10; NAGK; C11orf
  1. What is the species homology for "HSPD1 Antibody - C-terminal region (AVARP09014_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Rat, Guinea Pig, Rabbit".

  2. How long will it take to receive "HSPD1 Antibody - C-terminal region (AVARP09014_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "HSPD1 Antibody - C-terminal region (AVARP09014_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "HSPD1 Antibody - C-terminal region (AVARP09014_P050)"?

    This target may also be called "HLD4, CPN60, GROEL, HSP60, HSP65, SPG13, HSP-60, HuCHA60" in publications.

  5. What is the shipping cost for "HSPD1 Antibody - C-terminal region (AVARP09014_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "HSPD1 Antibody - C-terminal region (AVARP09014_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "HSPD1 Antibody - C-terminal region (AVARP09014_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "61kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "HSPD1 Antibody - C-terminal region (AVARP09014_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "HSPD1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "HSPD1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "HSPD1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "HSPD1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "HSPD1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "HSPD1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Write Your Own Review
You're reviewing:HSPD1 Antibody - C-terminal region (AVARP09014_P050)
Your Rating
We found other products you might like!