FCGR1A Antibody - middle region (OAAB02345)

Catalog No: OAAB02345

Size:400ul

Western blot analysis of FCGR1A Antibody (Center) in NCI-H460 cell lysates (35ug/lane). FCGR1A (arrow) was detected using the purified Pab.

FCGR1A is strongly supported by BioGPS gene expression data to be expressed in NCI-H460

FCGR1A Antibody (Center) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FCGR1A Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

FCGR1A Antibody (Center) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid PBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Host: Rabbit
• Application: WB, FC, IHC-P
• Additional Information: Function: High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.
  Cellular Location: Cell membrane; Single-pass type I membrane protein Note=Stabilized at the cell membrane through interaction with FCER1G.
  Tissue Location: Monocyte/macrophage specific.
• Reconstitution and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This FCGR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-245 amino acids from the Central region of human FCGR1A.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Application Info: WB: 1:1000
  IHC-P: 1:50~100
  FC: 1:10~50
• Other Applications Image 1 Data: FCGR1A Antibody (Center) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Target Info

• Gene Symbol: FCGR1A
• Alias Symbols: CD64, FCRI, CD64A, IGFR1
• NCBI Gene Id: 2209
• Protein Name: High affinity immunoglobulin gamma Fc receptor I
• Description of Target: FCGR1A encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1.
• Uniprot ID: P12314
• Protein Accession #: NP_000557.1
• Molecular Weight: 42632 Da