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Epigenetics

Epigenetics is the study of gene expression changes that result from processes that do not involve alteration of the DNA sequence. During embryogenesis, various epigenetic mechanisms play important roles in governing proper development, including chromatin remodeling and DNA methylation. Given that primary DNA sequences are not altered in a developing embryo, it is the epigenetic modifications that underlie the spatial and temporal control of gene expression. Hyper- and hypo-methylation of DNA can result in reduced and increased transcription of specific genes, respectively. Aberrant methylation patterns have been linked to the development and progression of a variety of cancers. Genomic imprinting is another epigenetic process that has been associated with human diseases, including Angelman Syndrome. Other epigenetic processes include histone acetylation and deacetylation, X chromosome inactivation, and heterochromatin regulation. While it is known that epigenetic changes can be maintained during cell division, evidence is mounting to support the notion that epigenetic marks can be transmitted from one generation to the next. Environmental factors such as stress and diet can have epigenetic consequences and these consequences may be passed on to offspring[1].

1. Waterland RA and Jirtle RL. 2003. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol. Aug;23(15):5293-300.

Epigenetics is study of inherited changes in phenotype (appearance) or gene expression caused by mechanisms other than changes in the underlying DNA sequence. We have manufactured about 400 products for proteins related to Epigenetic research.

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Showing 721 - 750 of 761
  Type Catalog # Product Product Images Price (USD)
  pAb ARP32470_T100 SUV39H1 antibody - C-terminal region (ARP32470_T100)
Reacts with
Cow; Dog; Guinea Pig; Human; Mouse; Rabbit; Rat; Zebrafish
Application
IHC, WB
$229.00
  pAb ARP49124_P050 DNMT3B antibody - middle region (ARP49124_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat; Zebrafish
Application
WB
$289.00
  pAb OAAB01373 PHB antibody - N-terminal region (OAAB01373)
Reacts with
Cow; Human
Application
WB, IHC, FC
$289.00
  pAb ARP32088_P050 Ywhae antibody - C-terminal region (ARP32088_P050)
Reacts with
Cow; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat; Sheep; Zebrafish
Application
IHC, WB
$289.00
  pAb ARP31944_P050 FOXA2 antibody - middle region (ARP31944_P050)
Reacts with
Dog; Horse; Human; Mouse; Pig; Rabbit; Rat
Application
WB
$289.00
  pAb P100898_P050 YY1 antibody - middle region (P100898_P050)
Reacts with
Cow; Dog; Human; Mouse; Rat; Zebrafish
Application
IHC, WB
$289.00
  pAb ARP48315_P050 PHB2 antibody - N-terminal region (ARP48315_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat; Yeast; Zebrafish
Application
WB
$289.00
  pAb ARP37224_T100 MYBBP1A antibody - C-terminal region (ARP37224_T100)
Reacts with
Guinea Pig; Mouse; Rat
Application
IHC, WB
$229.00
  pAb OAAB05353 BMI1 Antibody (OAAB05353)
Reacts with
Human
Application
WB, IHC, FC, ELISA
$289.00
  pAb ARP56220_P050 HIST2H2BF antibody - N-terminal region (ARP56220_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat
Application
CHIP, WB
$289.00
  pAb ARP31447_P050 HOXA5 antibody - middle region (ARP31447_P050)
Reacts with
Cow; Dog; Horse; Human; Mouse; Pig; Rabbit; Rat
Application
IHC, WB
$289.00
  pAb P100757_P050 CTCF antibody - N-terminal region (P100757_P050)
Reacts with
Cow; Dog; Horse; Human; Mouse; Rabbit; Rat
Application
CHIP, WB
$289.00
  pAb OAAB05872 SNRPD3 antibody - C-terminal region (OAAB05872)
Reacts with
Human
Application
WB, IHC, FC, ELISA
$289.00
  pAb ARP36645_P050 MCM3 antibody - C-terminal region (ARP36645_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Pig; Rabbit; Rat
Application
IHC, WB
$289.00
  pAb ARP41764_T100 GNAS antibody - N-terminal region (ARP41764_T100)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat
Application
WB
$229.00
  pAb ARP34171_P050 SMARCB1 antibody - N-terminal region (ARP34171_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rat
Application
IHC, WB
$289.00
  pAb OAAB01980 MAPK3 Antibody (OAAB01980)
Reacts with
Human
Application
WB, DB, ELISA
$289.00
  pAb ARP51333_P050 CDC45L antibody - C-terminal region (ARP51333_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat
Application
WB
$289.00
  pAb ARP45826_P050 CHAF1B antibody - N-terminal region (ARP45826_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Pig; Rabbit; Rat; Zebrafish
Application
WB
$289.00
  pAb ARP34721_T100 CBX3 antibody - middle region (ARP34721_T100)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat
Application
IHC, WB
$229.00
  pAb ARP32479_P050 NCOR1 antibody - N-terminal region (ARP32479_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rat; Yeast
Application
IHC, WB
$289.00
  pAb OAAB04925 PIK3CA Antibody (OAAB04925)
Reacts with
Cow; Human; Mouse
Application
WB, IHC, FC
$289.00
  pAb ARP44327_P050 COMT antibody - middle region (ARP44327_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Pig; Rabbit; Rat
Application
WB
$289.00
  pAb OAAB05169 PRKCA antibody - N-terminal region (OAAB05169)
Reacts with
Human; Mouse
Application
WB, IHC, FC, ELISA
$289.00
  pAb ARP37145_P050 SREBF1 antibody - N-terminal region (ARP37145_P050)
Reacts with
Mouse; Rat
Application
WB
$289.00
  pAb OAAB05772 CDC73 antibody - center region (OAAB05772)
Reacts with
Human
Application
WB, FC, IHC, ELISA
$289.00
  pAb ARP38681_T100 TRIM28 antibody - C-terminal region (ARP38681_T100)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat
Application
IHC, WB
$229.00
  pAb ARP46350_P050 CDT1 antibody - C-terminal region (ARP46350_P050)
Reacts with
Cow; Dog; Human; Mouse; Pig; Rabbit; Rat; Yeast
Application
IHC, WB
$289.00
  pAb ARP38530_T100 HDAC1 antibody - C-terminal region (ARP38530_T100)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat; Yeast; Zebrafish
Application
WB
$229.00
  pAb OAAB04209 PRKAA1 Antibody (OAAB04209)
Reacts with
Human
Application
WB, FC, IHC
$289.00

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Showing 721 - 750 of 761