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Epigenetics

Epigenetics is the study of gene expression changes that result from processes that do not involve alteration of the DNA sequence. During embryogenesis, various epigenetic mechanisms play important roles in governing proper development, including chromatin remodeling and DNA methylation. Given that primary DNA sequences are not altered in a developing embryo, it is the epigenetic modifications that underlie the spatial and temporal control of gene expression. Hyper- and hypo-methylation of DNA can result in reduced and increased transcription of specific genes, respectively. Aberrant methylation patterns have been linked to the development and progression of a variety of cancers. Genomic imprinting is another epigenetic process that has been associated with human diseases, including Angelman Syndrome. Other epigenetic processes include histone acetylation and deacetylation, X chromosome inactivation, and heterochromatin regulation. While it is known that epigenetic changes can be maintained during cell division, evidence is mounting to support the notion that epigenetic marks can be transmitted from one generation to the next. Environmental factors such as stress and diet can have epigenetic consequences and these consequences may be passed on to offspring[1].

1. Waterland RA and Jirtle RL. 2003. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol. Aug;23(15):5293-300.

Epigenetics is study of inherited changes in phenotype (appearance) or gene expression caused by mechanisms other than changes in the underlying DNA sequence. We have manufactured about 400 products for proteins related to Epigenetic research.

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Showing 721 - 740 of 740
  Type Catalog # Product Product Images Price (USD)
  pAb ARP30031_P050 SMARCA5 antibody - N-terminal region (ARP30031_P050)
Reacts with
Bovine, Human, Dog, Rat, Pig, Horse, Guinea pig, Mouse
Application
CHIP, WB
$289.00
  pAb ARP58280_P050 H2AFX antibody - N-terminal region (ARP58280_P050)
Reacts with
Zebrafish, Rat, Dog, Guinea pig, Human, Mouse, Bovine, Horse
Application
WB
$289.00
  pAb ARP39076_P050 BRD4 antibody - C-terminal region (ARP39076_P050)
Reacts with
Mouse, Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Human
Application
CHIP, IF, WB
$289.00
  pAb ARP40195_P050 PRMT2 antibody - N-terminal region (ARP40195_P050)
Reacts with
Human, Rat
Application
WB, CHIP
$289.00
  pAb OAAB04338 MGMT antibody - C terminal region (OAAB04338)
Reacts with
Human
Application
WB, IHC, FC, ELISA
$289.00
  pAb ARP32470_T100 SUV39H1 antibody - C-terminal region (ARP32470_T100)
Reacts with
Mouse, Rat, Human, Dog, Rabbit, Bovine, Guinea pig, Zebrafish
Application
IHC, WB
$229.00
  pAb ARP49124_P050 DNMT3B antibody - middle region (ARP49124_P050)
Reacts with
Pig, Human, Zebrafish, Bovine, Dog, Horse, Rabbit, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP40169_T100 MBD2 antibody - middle region (ARP40169_T100)
Reacts with
Bovine, Rat, Mouse, Pig, Horse, Dog, Rabbit, Guinea pig, Human, Zebrafish
Application
WB
$229.00
  pAb ARP38215_P050 SMARCA1 antibody - N-terminal region (ARP38215_P050)
Reacts with
Human, Dog, Horse, Bovine, Pig, Rat, Mouse, Rabbit
Application
CHIP, IHC, WB
$289.00
  pAb ARP33542_T100 ANKRD11 antibody - N-terminal region (ARP33542_T100)
Reacts with
Human, Mouse, Rat, Bovine, Horse, Rabbit, Dog, Guinea pig, Zebrafish
Application
IHC, WB
$229.00
  mAb AMM99021 5-Methylcytosine (Methyl-CpG) Antibody (Clone #: 33D3)(50ug)
Reacts with
Drosophila Melanogaster; Human; Arabidopsis; Zebra fish; Dog; Mouse; C.elegans; Rat; Pig; Chicken
Application
WB, ELISA, FC, IHC-FP, RIA
$199.00
  pAb ARP57967_P050 ERG antibody - N-terminal region (ARP57967_P050)
Reacts with
Bovine, Human, Mouse, Rat, Dog, Horse, Rabbit, Guinea pig, Yeast, Zebrafish
Application
WB
$289.00
  pAb OAAB02325 NASP antibody - N-terminal region (OAAB02325)
Reacts with
Human
Application
WB, FC, ELISA
$289.00
  pAb ARP31944_P050 FOXA2 antibody - middle region (ARP31944_P050)
Reacts with
Human, Dog, Pig, Horse, Mouse, Rat, Rabbit
Application
WB
$289.00
  pAb OAAB01352 EZH2 Antibody (OAAB01352)
Reacts with
Human
Application
WB, FC, IHC, ELISA
$289.00
  pAb ARP56220_P050 HIST2H2BF antibody - N-terminal region (ARP56220_P050)
Reacts with
Human, Bovine, Horse, Rabbit, Mouse, Rat, Guinea pig, Dog
Application
CHIP, WB
$289.00
  pAb P100898_P050 YY1 antibody - middle region (P100898_P050)
Reacts with
Bovine, Dog, Human, Mouse, Rat, Zebrafish
Application
IHC, WB
$289.00
  pAb ARP63969_P050 C19orf10 antibody - middle region (ARP63969_P050)
Reacts with
Dog, Horse, Rat, Human, Pig, Bovine, Mouse
Application
IHC, WB
$289.00
  pAb ARP48315_P050 PHB2 antibody - N-terminal region (ARP48315_P050)
Reacts with
Human, Dog, Mouse, Horse, Rabbit, Rat, Guinea pig, Bovine, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP37224_T100 MYBBP1A antibody - C-terminal region (ARP37224_T100)
Reacts with
Mouse, Rat, Guinea pig
Application
IHC, WB
$229.00

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Showing 721 - 740 of 740