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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Epigenetics

Epigenetics is the study of gene expression changes that result from processes that do not involve alteration of the DNA sequence. During embryogenesis, various epigenetic mechanisms play important roles in governing proper development, including chromatin remodeling and DNA methylation. Given that primary DNA sequences are not altered in a developing embryo, it is the epigenetic modifications that underlie the spatial and temporal control of gene expression. Hyper- and hypo-methylation of DNA can result in reduced and increased transcription of specific genes, respectively. Aberrant methylation patterns have been linked to the development and progression of a variety of cancers. Genomic imprinting is another epigenetic process that has been associated with human diseases, including Angelman Syndrome. Other epigenetic processes include histone acetylation and deacetylation, X chromosome inactivation, and heterochromatin regulation. While it is known that epigenetic changes can be maintained during cell division, evidence is mounting to support the notion that epigenetic marks can be transmitted from one generation to the next. Environmental factors such as stress and diet can have epigenetic consequences and these consequences may be passed on to offspring[1].

1. Waterland RA and Jirtle RL. 2003. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol. Aug;23(15):5293-300.

Epigenetics is study of inherited changes in phenotype (appearance) or gene expression caused by mechanisms other than changes in the underlying DNA sequence. We have manufactured about 400 products for proteins related to Epigenetic research.

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Showing 721 - 740 of 740
  Type Catalog # Product Product Images Price (USD)
  pAb OAAB01980 MAPK3 Antibody (OAAB01980)
Reacts with
Human
Application
WB, DB, ELISA
$289.00
  pAb ARP40196_T100 PRMT2 antibody - N-terminal region (ARP40196_T100)
Reacts with
Human, Pig, Horse, Mouse, Bovine, Rat, Dog, Rabbit, Guinea pig
Application
IHC, WB
$229.00
  pAb ARP34151_T100 ATF2 antibody - C-terminal region (ARP34151_T100)
Reacts with
Human, Bovine, Dog, Horse, Rabbit, Rat, Mouse, Guinea pig
Application
IHC, WB
$229.00
  pAb ARP58157_P050 HMGB2 antibody - middle region (ARP58157_P050)
Reacts with
Rat, Human, Dog, Bovine, Pig, Horse, Rabbit, Mouse, Guinea pig, Zebrafish
Application
IHC, WB
$289.00
  pAb ARP45772_T100 USP16 antibody - N-terminal region (ARP45772_T100)
Reacts with
Human, Dog, Horse, Bovine, Pig, Rabbit, Rat, Guinea pig, Mouse
Application
IHC, WB
$229.00
  pAb ARP39021_P050 UHRF1 antibody - N-terminal region (ARP39021_P050)
Reacts with
Human, Rat, Guinea pig, Bovine, Zebrafish, Mouse, Dog
Application
WB
$289.00
  pAb ARP34644_P050 PSIP1 antibody - middle region (ARP34644_P050)
Reacts with
Horse, Sheep, Bovine, Dog, Rat, Rabbit, Guinea pig, Human, Mouse
Application
WB
$289.00
  pAb ARP43599_T100 MTA2 antibody - C-terminal region (ARP43599_T100)
Reacts with
Horse, Rabbit, Human, Rat, Dog, Pig, Mouse, Goat, Bovine, Guinea pig
Application
IHC, WB
$229.00
  pAb ARP38954_P050 RERE antibody - N-terminal region (ARP38954_P050)
Reacts with
Mouse, Bovine, Horse, Rabbit, Rat, Guinea pig, Human, Yeast, Dog
Application
WB
$289.00
  pAb ARP31945_P050 FOXA3 antibody - middle region (ARP31945_P050)
Reacts with
Dog, Pig, Rat, Guinea pig, Human, Bovine, Horse, Mouse, Rabbit, Zebrafish
Application
IHC, WB
$289.00
  pAb ARP37905_P050 Mybbp1a antibody - C-terminal region (ARP37905_P050)
Reacts with
Mouse, Rat, Human
Application
WB
$289.00
  pAb OAAB04925 PIK3CA Antibody (OAAB04925)
Reacts with
Human
Application
WB, IHC, FC, ELISA
$289.00
  pAb ARP33028_T100 PHF1 antibody - C-terminal region (ARP33028_T100)
Reacts with
Bovine, Dog, Pig, Rabbit, Guinea pig, Human, Rat, Horse, Mouse
Application
IHC, WB
$229.00
  pAb ARP43025_T100 UBE2L3 antibody - C-terminal region (ARP43025_T100)
Reacts with
Zebrafish, Human, Rat, Pig, Dog, Bovine, Horse, Rabbit, Guinea pig, Mouse
Application
IHC, WB
$229.00
  pAb ARP38791_P050 HTATIP antibody - N-terminal region (ARP38791_P050)
Reacts with
Mouse, Human, Bovine, Dog, Pig, Horse, Goat, Rabbit, Rat, Guinea pig, Zebrafish
Application
IHC, WB
$289.00
  pAb ARP48316_P050 PHB2 antibody - C-terminal region (ARP48316_P050)
Reacts with
Mouse, Rabbit, Pig, Bovine, Rat, Human, Dog, Guinea pig
Application
WB
$289.00
  pAb OAAB05169 PRKCA antibody - N-terminal region (OAAB05169)
Reacts with
Human; Mouse
Application
WB, IHC, FC, ELISA
$289.00
  pAb OAAB05772 CDC73 antibody - center region (OAAB05772)
Reacts with
Human
Application
WB, FC, IHC, ELISA
$289.00
  pAb ARP42788_T100 HDAC9 antibody - C-terminal region (ARP42788_T100)
Reacts with
Human, Pig, Sheep, Guinea pig, Mouse
Application
CHIP, IHC, WB
$229.00
  pAb ARP31451_P050 HDAC6 antibody - N-terminal region (ARP31451_P050)
Reacts with
Human, Dog, Horse, Rabbit, Pig, Bovine, Rat, Guinea pig, Mouse
Application
CHIP, WB
$289.00

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Showing 721 - 740 of 740