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Epigenetics

Epigenetics is the study of gene expression changes that result from processes that do not involve alteration of the DNA sequence. During embryogenesis, various epigenetic mechanisms play important roles in governing proper development, including chromatin remodeling and DNA methylation. Given that primary DNA sequences are not altered in a developing embryo, it is the epigenetic modifications that underlie the spatial and temporal control of gene expression. Hyper- and hypo-methylation of DNA can result in reduced and increased transcription of specific genes, respectively. Aberrant methylation patterns have been linked to the development and progression of a variety of cancers. Genomic imprinting is another epigenetic process that has been associated with human diseases, including Angelman Syndrome. Other epigenetic processes include histone acetylation and deacetylation, X chromosome inactivation, and heterochromatin regulation. While it is known that epigenetic changes can be maintained during cell division, evidence is mounting to support the notion that epigenetic marks can be transmitted from one generation to the next. Environmental factors such as stress and diet can have epigenetic consequences and these consequences may be passed on to offspring[1].

1. Waterland RA and Jirtle RL. 2003. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol. Aug;23(15):5293-300.

Epigenetics is study of inherited changes in phenotype (appearance) or gene expression caused by mechanisms other than changes in the underlying DNA sequence. We have manufactured about 400 products for proteins related to Epigenetic research.

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Showing 601 - 630 of 738
  Type Catalog # Product Product Images Price (USD)
  pAb ARP58370_P050 CBX2 antibody - middle region (ARP58370_P050)
Reacts with
Human, Horse, Bovine, Pig, Rat
Application
WB
$289.00
  pAb ARP54490_P050 NARF antibody - middle region (ARP54490_P050)
Reacts with
Human, Bovine, Guinea pig, Rat, Mouse, Horse, Dog, Rabbit
Application
WB
$289.00
  pAb ARP65292_P050 AP1M1 antibody - C-terminal region (ARP65292_P050)
Reacts with
Human, Pig, Dog, Horse, Rabbit, Guinea pig, Zebrafish, Rat, Mouse, Bovine, Yeast
Application
WB
$289.00
  pAb ARP38539_P050 MECP2 antibody - middle region (ARP38539_P050)
Reacts with
Human, Horse, Rabbit, Dog, Rat, Bovine, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP34304_P050 SAP30BP antibody - N-terminal region (ARP34304_P050)
Reacts with
Rat, Human, Rabbit, Mouse, Pig, Horse, Guinea pig, Dog, Bovine
Application
IHC, WB
$289.00
  pAb ARP58283_P050 H2AFY antibody - middle region (ARP58283_P050)
Reacts with
Human, Pig, Rabbit, Rat, Bovine, Mouse, Dog, Horse, Guinea pig
Application
WB
$289.00
  pAb ARP64337_P050 RAB3C antibody - C-terminal region (ARP64337_P050)
Reacts with
Zebrafish, Bovine, Dog, Pig, Horse, Guinea pig, Mouse, Rat, Human, Sheep, Rabbit
Application
WB
$289.00
  pAb ARP46227_P050 NCAPH antibody - C-terminal region (ARP46227_P050)
Reacts with
Human, Rat, Dog, Pig, Rabbit, Mouse, Bovine, Guinea pig, Horse
Application
WB
$289.00
  pAb ARP39268_T100 JMJD1B antibody - C-terminal region (ARP39268_T100)
Reacts with
Mouse, Human, Rat, Bovine, Dog, Zebrafish, Pig, Horse, Rabbit, Guinea pig
Application
WB
$229.00
  pAb ARP36644_P050 MCM3 antibody - C-terminal region (ARP36644_P050)
Reacts with
Bovine, Human, Rabbit, Rat, Guinea pig, Dog, Horse, Mouse, Yeast
Application
IHC, WB
$289.00
  pAb OAAB06362 HDAC2 antibody - center region (OAAB06362)
Reacts with
Human
Application
WB, IHC, ELISA
$289.00
  pAb ARP32694_P050 MECP2 antibody - N-terminal region (ARP32694_P050)
Reacts with
Human, Horse, Rabbit, Mouse, Dog, Rat, Bovine, Guinea pig, Yeast
Application
WB
$289.00
  pAb ARP39788_P050 DACH1 antibody - C-terminal region (ARP39788_P050)
Reacts with
Horse, Rabbit, Rat, Guinea pig, Human, Zebrafish, Dog, Mouse
Application
WB
$289.00
  pAb ARP52046_P050 DFFB antibody - middle region (ARP52046_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP40731_P050 SF3B3 antibody - middle region (ARP40731_P050)
Reacts with
Bovine, Human, Mouse, Rat, Dog, Horse, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP51247_P050 Suv420h1 antibody - C-terminal region (ARP51247_P050)
Reacts with
Bovine, Dog, Mouse, Rat, Human, Horse, Guinea pig, Zebrafish, Rabbit
Application
CHIP, WB
$289.00
  pAb ARP34230_P050 HDAC4 antibody - middle region (ARP34230_P050)
Reacts with
Human, Bovine, Guinea pig, Mouse, Rat, Dog, Rabbit
Application
WB
$289.00
  pAb ARP33330_P050 SOX12 antibody - C-terminal region (ARP33330_P050)
Reacts with
Human, Rat, Dog, Horse, Pig, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP65075_P050 FKBP10 antibody - C-terminal region (ARP65075_P050)
Reacts with
Human, Mouse, Dog, Horse, Rabbit, Guinea pig, Bovine, Rat
Application
WB
$289.00
  pAb ARP46131_P050 SMC4 antibody - middle region (ARP46131_P050)
Reacts with
Human, Dog, Rat, Pig, Horse, Guinea pig, Bovine, Zebrafish, Mouse
Application
WB
$289.00
  pAb ARP39077_P050 PATZ1 antibody - N-terminal region (ARP39077_P050)
Reacts with
Human, Horse, Rabbit, Rat, Bovine, Dog, Pig, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP35742_P050 MTA2 antibody - N-terminal region (ARP35742_P050)
Reacts with
Rat, Dog, Pig, Horse, Goat, Rabbit, Guinea pig, Human, Bovine, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP32496_T100 GRIP1 antibody - N-terminal region (ARP32496_T100)
Reacts with
Mouse, Rat, Dog, Pig, Human, Horse, Rabbit, Guinea pig
Application
WB
$229.00
  pAb ARP53567_P050 LOC100362123 antibody - C-terminal region (ARP53567_P050)
Reacts with
Bovine, Human, Horse, Rat, Pig, Mouse, Rabbit, Zebrafish, Dog
Application
WB
$289.00
  pAb ARP51100_P050 MSL3L2 antibody - middle region (ARP51100_P050)
Reacts with
Human, Bovine, Dog, Pig, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP38260_T100 SUPT6H antibody - N-terminal region (ARP38260_T100)
Reacts with
Bovine, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Human, Mouse, Yeast, Zebrafish
Application
IHC, WB
$229.00
  pAb ARP45772_T100 USP16 antibody - N-terminal region (ARP45772_T100)
Reacts with
Human, Dog, Horse, Bovine, Pig, Rabbit, Rat, Guinea pig, Mouse
Application
IHC, WB
$229.00
  pAb ARP39021_P050 UHRF1 antibody - N-terminal region (ARP39021_P050)
Reacts with
Human, Rat, Guinea pig, Bovine, Zebrafish, Mouse, Dog
Application
WB
$289.00
  pAb ARP34644_P050 PSIP1 antibody - middle region (ARP34644_P050)
Reacts with
Horse, Sheep, Bovine, Dog, Rat, Rabbit, Guinea pig, Human, Mouse
Application
WB
$289.00
  pAb ARP37905_P050 Mybbp1a antibody - C-terminal region (ARP37905_P050)
Reacts with
Mouse, Rat, Human
Application
WB
$289.00

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Showing 601 - 630 of 738