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Epigenetics

Epigenetics is the study of gene expression changes that result from processes that do not involve alteration of the DNA sequence. During embryogenesis, various epigenetic mechanisms play important roles in governing proper development, including chromatin remodeling and DNA methylation. Given that primary DNA sequences are not altered in a developing embryo, it is the epigenetic modifications that underlie the spatial and temporal control of gene expression. Hyper- and hypo-methylation of DNA can result in reduced and increased transcription of specific genes, respectively. Aberrant methylation patterns have been linked to the development and progression of a variety of cancers. Genomic imprinting is another epigenetic process that has been associated with human diseases, including Angelman Syndrome. Other epigenetic processes include histone acetylation and deacetylation, X chromosome inactivation, and heterochromatin regulation. While it is known that epigenetic changes can be maintained during cell division, evidence is mounting to support the notion that epigenetic marks can be transmitted from one generation to the next. Environmental factors such as stress and diet can have epigenetic consequences and these consequences may be passed on to offspring[1].

1. Waterland RA and Jirtle RL. 2003. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol. Aug;23(15):5293-300.

Epigenetics is study of inherited changes in phenotype (appearance) or gene expression caused by mechanisms other than changes in the underlying DNA sequence. We have manufactured about 400 products for proteins related to Epigenetic research.

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Showing 601 - 630 of 753
  Type Catalog # Product Product Images Price (USD)
  pAb ARP65335_P050 LANCL1 antibody - N-terminal region (ARP65335_P050)
Reacts with
Mouse, Human, Pig, Horse, Rabbit, Rat, Guinea pig, Zebrafish, Dog, Bovine
Application
WB
$289.00
  pAb OAEB02378 BHMT Antibody (OAEB02378)
Reacts with
Bovine, Dog, Guinea pig, Human, Mouse, Pig, Rabbit, Rat
Application
WB
$289.00
  pAb ARP38523_P050 CIR antibody - C-terminal region (ARP38523_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34275_T100 ARID3B antibody - N-terminal region (ARP34275_T100)
Reacts with
Human, Dog, Pig, Horse, Mouse, Bovine, Guinea pig, Rat, Rabbit
Application
WB
$229.00
  pAb ARP58324_P050 SMARCD1 antibody - middle region (ARP58324_P050)
Reacts with
Human, Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP64202_P050 CLP1 antibody - N-terminal region (ARP64202_P050)
Reacts with
Bovine, Pig, Dog, Human, Horse, Rabbit, Rat, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP39339_P050 HMG20A antibody - N-terminal region (ARP39339_P050)
Reacts with
Human, Dog, Pig, Rat, Horse, Bovine, Rabbit
Application
WB
$289.00
  pAb OAAB01771 EP300 Antibody (Phospho-S1834) (OAAB01771)
Reacts with
Human
Application
WB, DB, IHC, ELISA
$289.00
  pAb ARP36649_T100 MCM4 antibody - middle region (ARP36649_T100)
Reacts with
Human, Bovine, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Mouse, Zebrafish
Application
WB
$229.00
  pAb OAAB06134 WAC antibody - center region (OAAB06134)
Reacts with
Human
Application
WB, FC, ELISA
$289.00
  pAb ARP32759_P050 HMG20A antibody - middle region (ARP32759_P050)
Reacts with
Human, Rat, Dog, Horse, Guinea pig, Mouse, Bovine, Rabbit
Application
WB
$289.00
  pAb ARP39331_P050 PBRM1 antibody - N-terminal region (ARP39331_P050)
Reacts with
Human, Mouse, Rat, Bovine, Dog, Horse, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP53228_P050 RGD1565997 antibody - N-terminal region (ARP53228_P050)
Reacts with
Rat, Horse, Rabbit, Guinea pig, Human, Dog, Bovine, Mouse
Application
WB
$289.00
  pAb ARP30434_P050 BRCA1 antibody - N-terminal region (ARP30434_P050)
Reacts with
Human, Dog, Horse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP51480_T100 HIST2H2AC antibody - middle region (ARP51480_T100)
Reacts with
Bovine, Rat, Dog, Pig, Mouse, Human, Rabbit, Guinea pig
Application
WB
$229.00
  pAb ARP40314_P050 RARA antibody - N-terminal region (ARP40314_P050)
Reacts with
Human, Rat, Mouse
Application
WB
$289.00
  pAb ARP38368_P050 SMARCA5 antibody - N-terminal region (ARP38368_P050)
Reacts with
Human, Horse
Application
WB
$289.00
  pAb ARP34172_P050 SMARCB1 antibody - middle region (ARP34172_P050)
Reacts with
Human, Dog, Pig, Rabbit, Rat, Guinea pig, Bovine, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP58206_P050 JHDM1D antibody - C region (ARP58206_P050)
Reacts with
Human, Rabbit, Dog, Rat, Mouse
Application
WB
$289.00
  pAb ARP65020_P050 GPM6A antibody - C-terminal region (ARP65020_P050)
Reacts with
Zebrafish, Dog, Horse, Rabbit, Bovine, Rat, Guinea pig, Mouse, Human
Application
WB
$289.00
  pAb ARP46156_P050 SMC2 antibody - middle region (ARP46156_P050)
Reacts with
Human, Rat, Rabbit, Mouse, Dog, Horse, Guinea pig, Zebrafish, Bovine
Application
WB
$289.00
  pAb ARP35799_P050 ZNF238 antibody - N-terminal region (ARP35799_P050)
Reacts with
Bovine, Human, Dog, Horse, Rabbit, Rat, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP32543_P050 MIZF antibody - middle region (ARP32543_P050)
Reacts with
Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Human, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP54706_P050 FDXR antibody - N-terminal region (ARP54706_P050)
Reacts with
Human, Pig, Mouse, Dog, Bovine, Horse, Rabbit, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP50384_P050 ARID3C antibody - C-terminal region (ARP50384_P050)
Reacts with
Human, Mouse, Rat, Dog, Pig, Rabbit, Bovine, Guinea pig
Application
WB
$289.00
  pAb OAAB04423 PRKAA2 antibody - C-terminal region (OAAB04423)
Reacts with
Human
Application
WB, IHC, ELISA
$289.00
  pAb ARP33754_T100 PARP1 antibody - C-terminal region (ARP33754_T100)
Reacts with
Human, Bovine, Dog, Horse, Rabbit, Rat, Guinea pig, Mouse, Zebrafish
Application
WB
$229.00
  pAb ARP33307_T100 SMARCC1 antibody - C-terminal region (ARP33307_T100)
Reacts with
Human, Rat, Mouse, Dog, Bovine, Horse, Pig, Guinea pig, Rabbit
Application
WB
$229.00
  pAb ARP65093_P050 NMUR1 antibody - C-terminal region (ARP65093_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP46043_P050 SMC2 antibody - N-terminal region (ARP46043_P050)
Reacts with
Human, Mouse, Rat, Dog, Bovine, Pig, Horse, Rabbit, Guinea pig, Zebrafish, Yeast
Application
WB
$289.00

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Showing 601 - 630 of 753