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Epigenetics

Epigenetics is the study of gene expression changes that result from processes that do not involve alteration of the DNA sequence. During embryogenesis, various epigenetic mechanisms play important roles in governing proper development, including chromatin remodeling and DNA methylation. Given that primary DNA sequences are not altered in a developing embryo, it is the epigenetic modifications that underlie the spatial and temporal control of gene expression. Hyper- and hypo-methylation of DNA can result in reduced and increased transcription of specific genes, respectively. Aberrant methylation patterns have been linked to the development and progression of a variety of cancers. Genomic imprinting is another epigenetic process that has been associated with human diseases, including Angelman Syndrome. Other epigenetic processes include histone acetylation and deacetylation, X chromosome inactivation, and heterochromatin regulation. While it is known that epigenetic changes can be maintained during cell division, evidence is mounting to support the notion that epigenetic marks can be transmitted from one generation to the next. Environmental factors such as stress and diet can have epigenetic consequences and these consequences may be passed on to offspring[1].

1. Waterland RA and Jirtle RL. 2003. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol. Aug;23(15):5293-300.

Epigenetics is study of inherited changes in phenotype (appearance) or gene expression caused by mechanisms other than changes in the underlying DNA sequence. We have manufactured about 400 products for proteins related to Epigenetic research.

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Showing 601 - 630 of 758
  Type Catalog # Product Product Images Price (USD)
  pAb ARP38044_P050 TADA2L antibody - N-terminal region (ARP38044_P050)
Reacts with
Human, Rat, Dog, Horse, Rabbit, Guinea pig, Mouse, Bovine
Application
WB
$289.00
  pAb ARP33347_P050 ING3 antibody - middle region (ARP33347_P050)
Reacts with
Human, Mouse, Bovine, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Zebrafish, Yeast
Application
IHC, WB
$289.00
  pAb ARP56875_P050 HP1BP3 antibody - middle region (ARP56875_P050)
Reacts with
Mouse, Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP65176_P050 LXN antibody - C-terminal region (ARP65176_P050)
Reacts with
Dog, Bovine, Horse, Goat, Rabbit, Guinea pig, Human, Mouse, Rat
Application
WB
$289.00
  pAb ARP38979_P050 HEY2 antibody - middle region (ARP38979_P050)
Reacts with
Human, Pig, Guinea pig, Bovine, Horse, Rat, Mouse, Dog, Rabbit, Zebrafish
Application
WB
$289.00
  pAb OAAB02263 SETD6 antibody - C-terminal region (OAAB02263)
Reacts with
Human
Application
WB, IHC
$289.00
  pAb ARP34514_T100 SMARCA3 antibody - N-terminal region (ARP34514_T100)
Reacts with
Human, Dog, Bovine, Horse, Rabbit, Mouse, Pig, Rat
Application
WB
$229.00
  pAb ARP32012_P050 MBD1 antibody - C-terminal region (ARP32012_P050)
Reacts with
Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Bovine, Mouse
Application
WB
$289.00
  pAb ARP62677_P050 LIMCH1 antibody - C-terminal region (ARP62677_P050)
Reacts with
Human, Dog, Rat, Rabbit, Mouse
Application
WB
$289.00
  pAb ARP31693_P050 SCMH1 antibody - middle region (ARP31693_P050)
Reacts with
Human, Bovine, Dog, Horse, Rabbit, Mouse, Rat, Yeast
Application
WB
$289.00
  pAb ARP63960_P050 STRA8 antibody - C-terminal region (ARP63960_P050)
Reacts with
Human, Dog, Pig
Application
WB
$289.00
  pAb ARP48526_P050 TRMT11 antibody - N-terminal region (ARP48526_P050)
Reacts with
Dog, Mouse, Rat, Human, Horse, Rabbit, Guinea pig, Bovine
Application
WB
$289.00
  pAb ARP39589_P050 PHF1 antibody - C-terminal region (ARP39589_P050)
Reacts with
Human, Bovine, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb OAAB01410 AHCY antibody - N-terminal region (OAAB01410)
Reacts with
Human
Application
WB, IHC, ELISA
$289.00
  pAb ARP37525_P050 CBFA2T2H antibody - middle region (ARP37525_P050)
Reacts with
Human, Rat, Mouse, Rabbit, Guinea pig, Bovine, Horse, Dog
Application
WB
$289.00
  pAb ARP33030_P050 PHF2 antibody - middle region (ARP33030_P050)
Reacts with
Human, Rabbit, Yeast, Bovine, Horse
Application
WB
$289.00
  pAb ARP37524_P050 Cbfa2t2 antibody - middle region (ARP37524_P050)
Reacts with
Rat, Mouse, Human, Bovine, Dog, Horse, Rabbit, Pig, Guinea pig
Application
WB
$289.00
  pAb ARP56543_P050 SFRP2 antibody - middle region (ARP56543_P050)
Reacts with
Human, Sheep, Dog, Pig, Horse, Rabbit, Rat, Mouse, Bovine, Guinea pig
Application
WB
$289.00
  pAb ARP65229_P050 COX7A1 antibody - N-terminal region (ARP65229_P050)
Reacts with
Human, Pig, Zebrafish, Horse, Dog, Bovine, Sheep, Rabbit, Mouse
Application
WB
$289.00
  pAb ARP43246_P050 MSL2L1 antibody - N-terminal region (ARP43246_P050)
Reacts with
Human, Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP38798_P050 ARID3B antibody - C-terminal region (ARP38798_P050)
Reacts with
Mouse, Rat, Bovine, Dog, Horse, Pig, Human, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP34468_T100 MIER1 antibody - middle region (ARP34468_T100)
Reacts with
Rat, Zebrafish, Dog, Horse, Rabbit, Guinea pig, Bovine, Mouse, Human
Application
WB
$229.00
  pAb ARP31460_P050 TRIM28 antibody - N-terminal region (ARP31460_P050)
Reacts with
Human, Dog, Rat, Mouse, Bovine
Application
WB
$289.00
  pAb P100799_P050 SSRP1 antibody - middle region (P100799_P050)
Reacts with
Bovine, Human, Mouse, Rat
Application
WB
$289.00
  pAb ARP64009_P050 COQ7 antibody - C-terminal region (ARP64009_P050)
Reacts with
Horse, Rat, Human, Dog, Guinea pig, Mouse, Bovine, Yeast, Rabbit
Application
WB
$289.00
  pAb ARP47638_P050 UBN1 antibody - C-terminal region (ARP47638_P050)
Reacts with
Bovine, Dog, Rat, Guinea pig, Human, Horse, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP39509_T100 FOXA2 antibody - C-terminal region (ARP39509_T100)
Reacts with
Human, Dog, Pig, Horse, Mouse, Rat, Bovine, Rabbit, Guinea pig
Application
WB
$229.00
  pAb OAAB01586 APEX1 antibody - N-terminal region (OAAB01586)
Reacts with
Human
Application
WB, ELISA
$289.00
  pAb ARP32907_P050 HR antibody - middle region (ARP32907_P050)
Reacts with
Human, Pig, Dog, Bovine, Mouse, Rat
Application
WB
$289.00
  pAb ARP58343_P050 TLK2 antibody - N-terminal region (ARP58343_P050)
Reacts with
Mouse, Human, Bovine, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00

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Showing 601 - 630 of 758