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Epigenetics

Epigenetics is the study of gene expression changes that result from processes that do not involve alteration of the DNA sequence. During embryogenesis, various epigenetic mechanisms play important roles in governing proper development, including chromatin remodeling and DNA methylation. Given that primary DNA sequences are not altered in a developing embryo, it is the epigenetic modifications that underlie the spatial and temporal control of gene expression. Hyper- and hypo-methylation of DNA can result in reduced and increased transcription of specific genes, respectively. Aberrant methylation patterns have been linked to the development and progression of a variety of cancers. Genomic imprinting is another epigenetic process that has been associated with human diseases, including Angelman Syndrome. Other epigenetic processes include histone acetylation and deacetylation, X chromosome inactivation, and heterochromatin regulation. While it is known that epigenetic changes can be maintained during cell division, evidence is mounting to support the notion that epigenetic marks can be transmitted from one generation to the next. Environmental factors such as stress and diet can have epigenetic consequences and these consequences may be passed on to offspring[1].

1. Waterland RA and Jirtle RL. 2003. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol. Aug;23(15):5293-300.

Epigenetics is study of inherited changes in phenotype (appearance) or gene expression caused by mechanisms other than changes in the underlying DNA sequence. We have manufactured about 400 products for proteins related to Epigenetic research.

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Showing 601 - 630 of 738
  Type Catalog # Product Product Images Price (USD)
  pAb ARP43265_P050 RNF20 antibody - middle region (ARP43265_P050)
Reacts with
Bovine, Dog, Pig, Rat, Guinea pig, Human, Mouse, Horse, Rabbit
Application
WB
$289.00
  pAb OAAB02940 EHMT2 antibody - N-terminal region (OAAB02940)
Reacts with
Human
Application
WB, FC, ELISA
$289.00
  pAb ARP34426_P050 CBX1 antibody - N-terminal region (ARP34426_P050)
Reacts with
Human, Rat, Dog, Pig, Horse, Rabbit, Bovine, Mouse, Yeast, Zebrafish
Application
WB
$289.00
  pAb ARP31479_P050 TADA3L antibody - middle region (ARP31479_P050)
Reacts with
Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Bovine, Mouse, Zebrafish
Application
WB
$289.00
  pAb P100861_P050 RARA antibody - middle region (P100861_P050)
Reacts with
Bovine, Dog, Human, Mouse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP63978_P050 BRMS1 antibody - C-terminal region (ARP63978_P050)
Reacts with
Dog, Human, Pig, Horse, Rat, Guinea pig, Sheep, Bovine, Mouse
Application
WB
$289.00
  pAb ARP47938_P050 DISC1 antibody - middle region (ARP47938_P050)
Reacts with
Human, Horse, Rat, Pig
Application
WB
$289.00
  pAb ARP39540_P050 ZNF335 antibody - middle region (ARP39540_P050)
Reacts with
Human, Rabbit, Bovine, Dog, Pig, Horse, Rat, Guinea pig
Application
WB
$289.00
  pAb OAAB01500 FOXP3 antibody - C-terminal region (OAAB01500)
Reacts with
Human; Mouse
Application
WB, IHC, ELISA
$289.00
  pAb ARP37167_T100 Mta2 antibody - N-terminal region (ARP37167_T100)
Reacts with
Rat, Dog, Pig, Horse, Rabbit, Bovine, Mouse, Goat, Guinea pig, Human, Yeast, Zebrafish
Application
WB
$229.00
  pAb ARP32917_T100 DMAP1 antibody - N-terminal region (ARP32917_T100)
Reacts with
Human, Dog, Horse, Rabbit, Guinea pig, Bovine, Mouse, Rat, Zebrafish
Application
WB
$229.00
  pAb ARP64033_P050 RAP2A antibody - N-terminal region (ARP64033_P050)
Reacts with
Bovine, Zebrafish, Sheep, Rat, Dog, Pig, Horse, Human, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP53316_P050 PLEKHA7 antibody - middle region (ARP53316_P050)
Reacts with
Human, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Bovine, Rat
Application
WB
$289.00
  pAb ARP55315_P050 IRF2BP1 antibody - middle region (ARP55315_P050)
Reacts with
Human, Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP65232_P050 DDA1 antibody - middle region (ARP65232_P050)
Reacts with
Rat, Guinea pig, Bovine, Human, Mouse, Dog, Horse
Application
WB
$289.00
  pAb ARP42793_P050 HDAC9 antibody - middle region (ARP42793_P050)
Reacts with
Human, Dog, Rat, Bovine, Zebrafish, Pig, Horse, Sheep, Guinea pig, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP38539_P050 MECP2 antibody - middle region (ARP38539_P050)
Reacts with
Human, Horse, Rabbit, Dog, Rat, Bovine, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP34304_P050 SAP30BP antibody - N-terminal region (ARP34304_P050)
Reacts with
Rat, Human, Rabbit, Mouse, Pig, Horse, Guinea pig, Dog, Bovine
Application
IHC, WB
$289.00
  pAb P100625_T100 ERG antibody - middle region (P100625_T100)
Reacts with
Bovine, Dog, Guinea pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
$229.00
  pAb ARP64078_P050 ST6GAL1 antibody - C-terminal region (ARP64078_P050)
Reacts with
Human, Pig, Rat, Dog, Goat, Bovine, Horse, Sheep, Mouse, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP39381_T100 DMAP1 antibody - C-terminal region (ARP39381_T100)
Reacts with
Human, Zebrafish, Dog, Rabbit, Rat, Guinea pig, Bovine, Mouse
Application
WB
$229.00
  pAb ARP36662_T100 MCM4 antibody - N-terminal region (ARP36662_T100)
Reacts with
Human, Horse, Rabbit, Rat, Guinea pig, Mouse, Dog, Bovine
Application
WB
$229.00
  pAb ARP32833_P050 MSL3L1 antibody - middle region (ARP32833_P050)
Reacts with
Human, Guinea pig, Rat, Bovine, Dog, Horse, Mouse
Application
WB
$289.00
  pAb ARP58370_P050 CBX2 antibody - middle region (ARP58370_P050)
Reacts with
Human, Horse, Bovine, Pig, Rat
Application
WB
$289.00
  pAb ARP54490_P050 NARF antibody - middle region (ARP54490_P050)
Reacts with
Human, Bovine, Guinea pig, Rat, Mouse, Horse, Dog, Rabbit
Application
WB
$289.00
  pAb ARP65292_P050 AP1M1 antibody - C-terminal region (ARP65292_P050)
Reacts with
Human, Pig, Dog, Horse, Rabbit, Guinea pig, Zebrafish, Rat, Mouse, Bovine, Yeast
Application
WB
$289.00
  pAb ARP38479_P050 FOXA1 antibody - N-terminal region (ARP38479_P050)
Reacts with
Human, Dog, Bovine, Pig, Rat, Mouse, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP30080_T100 L3MBTL2 antibody - C-terminal region (ARP30080_T100)
Reacts with
Dog, Horse, Rabbit, Guinea pig, Bovine, Human, Rat, Mouse
Application
IHC, WB
$229.00
  pAb ARP40196_T100 PRMT2 antibody - N-terminal region (ARP40196_T100)
Reacts with
Human, Pig, Horse, Mouse, Bovine, Rat, Dog, Rabbit, Guinea pig
Application
IHC, WB
$229.00
  pAb ARP34151_T100 ATF2 antibody - C-terminal region (ARP34151_T100)
Reacts with
Human, Bovine, Dog, Horse, Rabbit, Rat, Mouse, Guinea pig
Application
IHC, WB
$229.00

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Showing 601 - 630 of 738