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Epigenetics

Epigenetics is the study of gene expression changes that result from processes that do not involve alteration of the DNA sequence. During embryogenesis, various epigenetic mechanisms play important roles in governing proper development, including chromatin remodeling and DNA methylation. Given that primary DNA sequences are not altered in a developing embryo, it is the epigenetic modifications that underlie the spatial and temporal control of gene expression. Hyper- and hypo-methylation of DNA can result in reduced and increased transcription of specific genes, respectively. Aberrant methylation patterns have been linked to the development and progression of a variety of cancers. Genomic imprinting is another epigenetic process that has been associated with human diseases, including Angelman Syndrome. Other epigenetic processes include histone acetylation and deacetylation, X chromosome inactivation, and heterochromatin regulation. While it is known that epigenetic changes can be maintained during cell division, evidence is mounting to support the notion that epigenetic marks can be transmitted from one generation to the next. Environmental factors such as stress and diet can have epigenetic consequences and these consequences may be passed on to offspring[1].

1. Waterland RA and Jirtle RL. 2003. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol. Aug;23(15):5293-300.

Epigenetics is study of inherited changes in phenotype (appearance) or gene expression caused by mechanisms other than changes in the underlying DNA sequence. We have manufactured about 400 products for proteins related to Epigenetic research.

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Showing 1 - 22 of 22
  Type Catalog # Product Product Images Price (USD)
  pAb ARP68362_P050 FRA10AC1 Antibody - C-terminal region (ARP68362_P050)
Reacts with
Human
Application
WB
$289.00
  pAb OAAB03601 FOS antibody - C-terminal region (OAAB03601)
Reacts with
Human
Application
WB, ELISA
$289.00
  pAb OAAB01501 FOXP3 antibody - center region (OAAB01501)
Reacts with
Human
Application
WB, ELISA
$289.00
  pAb OAEB01238 Fto Antibody (OAEB01238)
Reacts with
Bovine, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep
Application
WB
$289.00
  pAb ARP63726_P050 FGF19 antibody - C-terminal region (ARP63726_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP39509_T100 FOXA2 antibody - C-terminal region (ARP39509_T100)
Reacts with
Human, Dog, Pig, Horse, Mouse, Rat, Bovine, Rabbit, Guinea pig
Application
WB
$229.00
  pAb ARP60781_P050 FDPS antibody - C-terminal region (ARP60781_P050)
Reacts with
Pig, Dog, Horse, Rabbit, Human, Rat, Bovine, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP54612_P050 FKBP3 antibody - C-terminal region (ARP54612_P050)
Reacts with
Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Bovine, Human, Mouse, Zebrafish
Application
WB
$289.00
  pAb OAAB01500 FOXP3 antibody - C-terminal region (OAAB01500)
Reacts with
Human; Mouse
Application
WB, IHC, ELISA
$289.00
  pAb ARP54509_P050 FAM133B antibody - C-terminal region (ARP54509_P050)
Reacts with
Zebrafish, Human, Pig, Horse, Dog, Yeast, Bovine, Rat, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP39508_T100 FOXA2 antibody - N-terminal region (ARP39508_T100)
Reacts with
Human, Dog, Pig, Rabbit, Mouse, Rat, Guinea pig, Bovine, Zebrafish
Application
WB
$229.00
  pAb ARP37060_P050 Foxa2 antibody - middle region (ARP37060_P050)
Reacts with
Human, Mouse, Rat, Dog, Bovine, Pig, Horse, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP65075_P050 FKBP10 antibody - C-terminal region (ARP65075_P050)
Reacts with
Human, Mouse, Dog, Horse, Rabbit, Guinea pig, Bovine, Rat
Application
WB
$289.00
  pAb ARP45209_P050 FMO4 antibody - N-terminal region (ARP45209_P050)
Reacts with
Horse, Rat, Bovine, Guinea pig, Human, Mouse, Dog, Rabbit
Application
WB
$289.00
  pAb ARP54706_P050 FDXR antibody - N-terminal region (ARP54706_P050)
Reacts with
Human, Pig, Mouse, Dog, Bovine, Horse, Rabbit, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP57867_P050 FOXA1 antibody - N-terminal region (ARP57867_P050)
Reacts with
Dog, Rat, Bovine, Pig, Human, Mouse
Application
WB
$289.00
  pAb ARP65080_P050 FUZ antibody - C-terminal region (ARP65080_P050)
Reacts with
Human, Horse, Bovine, Pig, Mouse, Rat
Application
WB
$289.00
  pAb ARP32630_P050 FOXA1 antibody - C-terminal region (ARP32630_P050)
Reacts with
Human, Rat, Bovine, Pig, Dog, Guinea pig, Mouse, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP31945_P050 FOXA3 antibody - middle region (ARP31945_P050)
Reacts with
Dog, Pig, Rat, Guinea pig, Human, Bovine, Horse, Mouse, Rabbit, Zebrafish
Application
IHC, WB
$289.00
  pAb OAAB04099 FTO antibody - N-terminal region (OAAB04099)
Reacts with
Human
Application
WB, IHC, FC, ELISA
$289.00
  pAb ARP31944_P050 FOXA2 antibody - middle region (ARP31944_P050)
Reacts with
Human, Dog, Pig, Horse, Mouse, Rat, Rabbit
Application
WB
$289.00
  pAb ARP38479_P050 FOXA1 antibody - N-terminal region (ARP38479_P050)
Reacts with
Human, Dog, Bovine, Pig, Rat, Mouse, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
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