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Epigenetics

Epigenetics is the study of gene expression changes that result from processes that do not involve alteration of the DNA sequence. During embryogenesis, various epigenetic mechanisms play important roles in governing proper development, including chromatin remodeling and DNA methylation. Given that primary DNA sequences are not altered in a developing embryo, it is the epigenetic modifications that underlie the spatial and temporal control of gene expression. Hyper- and hypo-methylation of DNA can result in reduced and increased transcription of specific genes, respectively. Aberrant methylation patterns have been linked to the development and progression of a variety of cancers. Genomic imprinting is another epigenetic process that has been associated with human diseases, including Angelman Syndrome. Other epigenetic processes include histone acetylation and deacetylation, X chromosome inactivation, and heterochromatin regulation. While it is known that epigenetic changes can be maintained during cell division, evidence is mounting to support the notion that epigenetic marks can be transmitted from one generation to the next. Environmental factors such as stress and diet can have epigenetic consequences and these consequences may be passed on to offspring[1].

1. Waterland RA and Jirtle RL. 2003. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol. Aug;23(15):5293-300.

Epigenetics is study of inherited changes in phenotype (appearance) or gene expression caused by mechanisms other than changes in the underlying DNA sequence. We have manufactured about 400 products for proteins related to Epigenetic research.

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Showing 1 - 30 of 758
  Type Catalog # Product Product Images Price (USD)
  pAb OAAB04925 PIK3CA Antibody (OAAB04925)
Reacts with
Human, Mouse
Application
WB, IHC, FC
$289.00
  pAb ARP44327_P050 COMT antibody - middle region (ARP44327_P050)
Reacts with
Bovine, Human, Pig, Horse, Rat, Mouse, Guinea pig, Rabbit, Dog
Application
WB
$289.00
  pAb OAAB05169 PRKCA antibody - N-terminal region (OAAB05169)
Reacts with
Human; Mouse
Application
WB, IHC, FC, ELISA
$289.00
  pAb ARP37145_P050 SREBF1 antibody - N-terminal region (ARP37145_P050)
Reacts with
Mouse, Rat
Application
WB
$289.00
  pAb OAAB05772 CDC73 antibody - center region (OAAB05772)
Reacts with
Human
Application
WB, FC, IHC, ELISA
$289.00
  pAb ARP38681_T100 TRIM28 antibody - C-terminal region (ARP38681_T100)
Reacts with
Human, Bovine, Dog, Horse, Rabbit, Rat, Guinea pig, Mouse
Application
IHC, WB
$229.00
  pAb ARP38530_T100 HDAC1 antibody - C-terminal region (ARP38530_T100)
Reacts with
Human, Mouse, Rat, Dog, Pig, Guinea pig, Bovine, Horse, Yeast, Rabbit, Zebrafish
Application
WB
$229.00
  pAb ARP46350_P050 CDT1 antibody - C-terminal region (ARP46350_P050)
Reacts with
Human, Rat, Pig, Mouse, Bovine, Rabbit, Yeast, Dog
Application
IHC, WB
$289.00
  pAb OAAB04209 PRKAA1 Antibody (OAAB04209)
Reacts with
Human
Application
WB, FC, IHC
$289.00
  pAb ARP34202_P050 ASH2L antibody - middle region (ARP34202_P050)
Reacts with
Human, Mouse, Rat, Dog, Horse, Guinea pig, Rabbit, Bovine
Application
IHC, WB
$289.00
  pAb ARP32630_P050 FOXA1 antibody - C-terminal region (ARP32630_P050)
Reacts with
Human, Rat, Bovine, Pig, Dog, Guinea pig, Mouse, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP32618_P050 HDAC2 antibody - C-terminal region (ARP32618_P050)
Reacts with
Human, Bovine, Dog, Pig, Rabbit, Rat, Mouse, Horse, Guinea pig, Yeast
Application
IHC, WB
$289.00
  pAb ARP38224_P050 SMARCE1 antibody - N-terminal region (ARP38224_P050)
Reacts with
Bovine, Human, Mouse, Dog, Zebrafish, Pig, Horse, Rabbit, Rat, Guinea pig
Application
IHC, WB
$289.00
  pAb ARP46122_P050 HIST1H1C antibody - middle region (ARP46122_P050)
Reacts with
Human, Guinea pig, Dog, Horse, Bovine, Rat, Mouse, Rabbit
Application
CHIP, WB
$289.00
  pAb ARP32485_P050 MBD2 antibody - N-terminal region (ARP32485_P050)
Reacts with
Rat, Human, Mouse
Application
WB
$289.00
  pAb ARP49096_P050 CDYL antibody - N-terminal region (ARP49096_P050)
Reacts with
Dog, Horse, Human, Bovine, Rabbit, Guinea pig, Rat, Mouse
Application
IF, WB
$289.00
  pAb ARP65151_P050 TNK1 antibody - C-terminal region (ARP65151_P050)
Reacts with
Yeast, Human, Pig, Guinea pig, Rabbit
Application
WB
$289.00
  pAb ARP39005_P050 IKZF3 antibody - C-terminal region (ARP39005_P050)
Reacts with
Bovine, Human, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP33338_P050 BRCA1 antibody - middle region (ARP33338_P050)
Reacts with
Human, Rat, Mouse, Bovine
Application
IHC, WB
$289.00
  pAb ARP31939_P050 HMGB2 antibody - C-terminal region (ARP31939_P050)
Reacts with
Rat, Dog, Bovine, Pig, Horse, Rabbit, Guinea pig, Human, Mouse, Zebrafish
Application
IHC, WB
$289.00
  pAb ARP64034_P050 SFTPA2 antibody - N-terminal region (ARP64034_P050)
Reacts with
Human, Bovine, Pig, Sheep, Dog, Goat, Rat, Horse, Guinea pig, Rabbit, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP38723_P050 ZBTB16 antibody - C-terminal region (ARP38723_P050)
Reacts with
Mouse, Horse, Dog, Rabbit, Rat, Guinea pig, Goat, Human, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP46357_P050 LMNB2 antibody - middle region (ARP46357_P050)
Reacts with
Rat, Bovine, Dog, Horse, Guinea pig, Human, Mouse, Zebrafish, Rabbit
Application
WB
$289.00
  pAb ARP42211_T100 RAD23A antibody - middle region (ARP42211_T100)
Reacts with
Bovine, Human, Dog, Pig, Horse, Mouse, Rabbit, Rat, Guinea pig
Application
IHC, WB
$229.00
  pAb ARP38479_P050 FOXA1 antibody - N-terminal region (ARP38479_P050)
Reacts with
Human, Dog, Bovine, Pig, Rat, Mouse, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb OAAB04099 FTO antibody - N-terminal region (OAAB04099)
Reacts with
Human
Application
WB, IHC, FC, ELISA
$289.00
  pAb ARP30080_T100 L3MBTL2 antibody - C-terminal region (ARP30080_T100)
Reacts with
Dog, Horse, Rabbit, Guinea pig, Bovine, Human, Rat, Mouse
Application
IHC, WB
$229.00
  pAb ARP40196_T100 PRMT2 antibody - N-terminal region (ARP40196_T100)
Reacts with
Human, Pig, Horse, Mouse, Bovine, Rat, Dog, Rabbit, Guinea pig
Application
IHC, WB
$229.00
  pAb OAAB04338 MGMT antibody - C terminal region (OAAB04338)
Reacts with
Human
Application
WB, IHC, FC, ELISA
$289.00
  pAb ARP34151_T100 ATF2 antibody - C-terminal region (ARP34151_T100)
Reacts with
Human, Bovine, Dog, Horse, Rabbit, Rat, Mouse, Guinea pig
Application
IHC, WB
$229.00

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Showing 1 - 30 of 758