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Epigenetics

Epigenetics is the study of gene expression changes that result from processes that do not involve alteration of the DNA sequence. During embryogenesis, various epigenetic mechanisms play important roles in governing proper development, including chromatin remodeling and DNA methylation. Given that primary DNA sequences are not altered in a developing embryo, it is the epigenetic modifications that underlie the spatial and temporal control of gene expression. Hyper- and hypo-methylation of DNA can result in reduced and increased transcription of specific genes, respectively. Aberrant methylation patterns have been linked to the development and progression of a variety of cancers. Genomic imprinting is another epigenetic process that has been associated with human diseases, including Angelman Syndrome. Other epigenetic processes include histone acetylation and deacetylation, X chromosome inactivation, and heterochromatin regulation. While it is known that epigenetic changes can be maintained during cell division, evidence is mounting to support the notion that epigenetic marks can be transmitted from one generation to the next. Environmental factors such as stress and diet can have epigenetic consequences and these consequences may be passed on to offspring[1].

1. Waterland RA and Jirtle RL. 2003. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol. Aug;23(15):5293-300.

Epigenetics is study of inherited changes in phenotype (appearance) or gene expression caused by mechanisms other than changes in the underlying DNA sequence. We have manufactured about 400 products for proteins related to Epigenetic research.

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Showing 1 - 30 of 740
  Type Catalog # Product Product Images Price (USD)
  pAb ARP43602_P050 Hdac4 Antibody - C-terminal region (ARP43602_P050)
Reacts with
Human, Bovine, Dog, Zebrafish, Rat, Guinea pig, Mouse, Yeast, Horse
Application
CHIP, WB
$289.00
  pAb ARP34202_P050 ASH2L antibody - middle region (ARP34202_P050)
Reacts with
Human, Mouse, Rat, Dog, Horse, Guinea pig, Rabbit, Bovine
Application
IHC, WB
$289.00
  pAb ARP32630_P050 FOXA1 antibody - C-terminal region (ARP32630_P050)
Reacts with
Human, Rat, Bovine, Pig, Dog, Guinea pig, Mouse, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP65019_P050 GPM6A antibody - C-terminal region (ARP65019_P050)
Reacts with
Dog, Horse, Zebrafish, Rabbit, Bovine, Rat, Guinea pig, Mouse, Human
Application
IHC, WB
$289.00
  pAb ARP32618_P050 HDAC2 antibody - C-terminal region (ARP32618_P050)
Reacts with
Human, Bovine, Dog, Pig, Rabbit, Rat, Mouse, Horse, Guinea pig, Yeast
Application
IHC, WB
$289.00
  pAb ARP32485_P050 MBD2 antibody - N-terminal region (ARP32485_P050)
Reacts with
Rat, Human, Mouse
Application
WB
$289.00
  pAb ARP38224_P050 SMARCE1 antibody - N-terminal region (ARP38224_P050)
Reacts with
Bovine, Human, Mouse, Dog, Zebrafish, Pig, Horse, Rabbit, Rat, Guinea pig
Application
IHC, WB
$289.00
  pAb OAAB04365 BCOR antibody - center region (OAAB04365)
Reacts with
Human; Mouse
Application
WB, IHC, ELISA
$289.00
  pAb ARP46122_P050 HIST1H1C antibody - middle region (ARP46122_P050)
Reacts with
Human, Guinea pig, Dog, Horse, Bovine, Rat, Mouse, Rabbit
Application
CHIP, WB
$289.00
  pAb ARP49096_P050 CDYL antibody - N-terminal region (ARP49096_P050)
Reacts with
Dog, Horse, Human, Bovine, Rabbit, Guinea pig, Rat, Mouse
Application
IF, WB
$289.00
  pAb OAAB01279 RUVBL1 Antibody (OAAB01279)
Reacts with
Human
Application
WB, FC, IHC, ELISA
$289.00
  pAb ARP39005_P050 IKZF3 antibody - C-terminal region (ARP39005_P050)
Reacts with
Bovine, Human, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP31939_P050 HMGB2 antibody - C-terminal region (ARP31939_P050)
Reacts with
Rat, Dog, Bovine, Pig, Horse, Rabbit, Guinea pig, Human, Mouse, Zebrafish
Application
IHC, WB
$289.00
  pAb OAAB01373 PHB antibody - N-terminal region (OAAB01373)
Reacts with
Human
Application
WB, IHC, FC, ELISA
$289.00
  pAb ARP33338_P050 BRCA1 antibody - middle region (ARP33338_P050)
Reacts with
Human, Rat, Mouse, Bovine
Application
IHC, WB
$289.00
  pAb ARP32088_P050 Ywhae antibody - C-terminal region (ARP32088_P050)
Reacts with
Human, Horse, Rabbit, Rat, Guinea pig, Mouse, Bovine, Sheep, Zebrafish
Application
IHC, WB
$289.00
  pAb ARP38723_P050 ZBTB16 antibody - C-terminal region (ARP38723_P050)
Reacts with
Mouse, Horse, Dog, Rabbit, Rat, Guinea pig, Goat, Human, Bovine, Zebrafish
Application
WB
$289.00
  pAb OAAB05353 BMI1 Antibody (OAAB05353)
Reacts with
Human
Application
WB, IHC, FC, ELISA
$289.00
  pAb ARP42211_T100 RAD23A antibody - middle region (ARP42211_T100)
Reacts with
Bovine, Human, Dog, Pig, Horse, Mouse, Rabbit, Rat, Guinea pig
Application
IHC, WB
$229.00
  pAb ARP31200_P050 ISGF3G antibody - N-terminal region (ARP31200_P050)
Reacts with
Human, Mouse, Bovine, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Zebrafish
Application
IHC, WB
$289.00
  pAb ARP46357_P050 LMNB2 antibody - middle region (ARP46357_P050)
Reacts with
Rat, Bovine, Dog, Horse, Guinea pig, Human, Mouse, Zebrafish, Rabbit
Application
WB
$289.00
  pAb OAAB05872 SNRPD3 antibody - C-terminal region (OAAB05872)
Reacts with
Human
Application
WB, IHC, FC, ELISA
$289.00
  pAb ARP38479_P050 FOXA1 antibody - N-terminal region (ARP38479_P050)
Reacts with
Human, Dog, Bovine, Pig, Rat, Mouse, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP30080_T100 L3MBTL2 antibody - C-terminal region (ARP30080_T100)
Reacts with
Dog, Horse, Rabbit, Guinea pig, Bovine, Human, Rat, Mouse
Application
IHC, WB
$229.00
  pAb ARP40196_T100 PRMT2 antibody - N-terminal region (ARP40196_T100)
Reacts with
Human, Pig, Horse, Mouse, Bovine, Rat, Dog, Rabbit, Guinea pig
Application
IHC, WB
$229.00
  pAb ARP34151_T100 ATF2 antibody - C-terminal region (ARP34151_T100)
Reacts with
Human, Bovine, Dog, Horse, Rabbit, Rat, Mouse, Guinea pig
Application
IHC, WB
$229.00
  pAb ARP58157_P050 HMGB2 antibody - middle region (ARP58157_P050)
Reacts with
Rat, Human, Dog, Bovine, Pig, Horse, Rabbit, Mouse, Guinea pig, Zebrafish
Application
IHC, WB
$289.00
  pAb OAAB01980 MAPK3 Antibody (OAAB01980)
Reacts with
Human
Application
WB, DB, ELISA
$289.00
  pAb ARP34644_P050 PSIP1 antibody - middle region (ARP34644_P050)
Reacts with
Horse, Sheep, Bovine, Dog, Rat, Rabbit, Guinea pig, Human, Mouse
Application
WB
$289.00
  pAb ARP45772_T100 USP16 antibody - N-terminal region (ARP45772_T100)
Reacts with
Human, Dog, Horse, Bovine, Pig, Rabbit, Rat, Guinea pig, Mouse
Application
IHC, WB
$229.00

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Showing 1 - 30 of 740