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Epigenetics

Epigenetics is the study of gene expression changes that result from processes that do not involve alteration of the DNA sequence. During embryogenesis, various epigenetic mechanisms play important roles in governing proper development, including chromatin remodeling and DNA methylation. Given that primary DNA sequences are not altered in a developing embryo, it is the epigenetic modifications that underlie the spatial and temporal control of gene expression. Hyper- and hypo-methylation of DNA can result in reduced and increased transcription of specific genes, respectively. Aberrant methylation patterns have been linked to the development and progression of a variety of cancers. Genomic imprinting is another epigenetic process that has been associated with human diseases, including Angelman Syndrome. Other epigenetic processes include histone acetylation and deacetylation, X chromosome inactivation, and heterochromatin regulation. While it is known that epigenetic changes can be maintained during cell division, evidence is mounting to support the notion that epigenetic marks can be transmitted from one generation to the next. Environmental factors such as stress and diet can have epigenetic consequences and these consequences may be passed on to offspring[1].

1. Waterland RA and Jirtle RL. 2003. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol. Aug;23(15):5293-300.

Epigenetics is study of inherited changes in phenotype (appearance) or gene expression caused by mechanisms other than changes in the underlying DNA sequence. We have manufactured about 400 products for proteins related to Epigenetic research.

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Showing 1 - 30 of 740
  Type Catalog # Product Product Images Price (USD)
  pAb OAAB05169 PRKCA antibody - N-terminal region (OAAB05169)
Reacts with
Human; Mouse
Application
WB, IHC, FC, ELISA
$289.00
  pAb ARP33028_T100 PHF1 antibody - C-terminal region (ARP33028_T100)
Reacts with
Bovine, Dog, Pig, Rabbit, Guinea pig, Human, Rat, Horse, Mouse
Application
IHC, WB
$229.00
  pAb ARP43025_T100 UBE2L3 antibody - C-terminal region (ARP43025_T100)
Reacts with
Zebrafish, Human, Rat, Pig, Dog, Bovine, Horse, Rabbit, Guinea pig, Mouse
Application
IHC, WB
$229.00
  pAb ARP38791_P050 HTATIP antibody - N-terminal region (ARP38791_P050)
Reacts with
Mouse, Human, Bovine, Dog, Pig, Horse, Goat, Rabbit, Rat, Guinea pig, Zebrafish
Application
IHC, WB
$289.00
  pAb ARP48316_P050 PHB2 antibody - C-terminal region (ARP48316_P050)
Reacts with
Mouse, Rabbit, Pig, Bovine, Rat, Human, Dog, Guinea pig
Application
WB
$289.00
  pAb OAAB05772 CDC73 antibody - center region (OAAB05772)
Reacts with
Human
Application
WB, FC, IHC, ELISA
$289.00
  pAb ARP42788_T100 HDAC9 antibody - C-terminal region (ARP42788_T100)
Reacts with
Human, Pig, Sheep, Guinea pig, Mouse
Application
CHIP, IHC, WB
$229.00
  pAb ARP31451_P050 HDAC6 antibody - N-terminal region (ARP31451_P050)
Reacts with
Human, Dog, Horse, Rabbit, Pig, Bovine, Rat, Guinea pig, Mouse
Application
CHIP, WB
$289.00
  pAb ARP46323_P050 CENPM antibody - middle region (ARP46323_P050)
Reacts with
Human, Pig, Horse, Rabbit, Dog, Bovine
Application
IF, WB
$289.00
  pAb ARP41962_T100 APCS antibody - N-terminal region (ARP41962_T100)
Reacts with
Human, Rat, Guinea pig, Mouse
Application
IHC, WB
$229.00
  pAb ARP30206_T100 RAD17 antibody - C-terminal region (ARP30206_T100)
Reacts with
Human, Bovine, Pig, Dog, Rat, Mouse
Application
WB
$229.00
  pAb ARP32627_P050 HMGN1 antibody - middle region (ARP32627_P050)
Reacts with
Human, Dog, Horse, Rat, Bovine, Rabbit, Pig, Guinea pig, Mouse
Application
IHC, WB
$289.00
  pAb ARP39080_T100 AKAP8L antibody - C-terminal region (ARP39080_T100)
Reacts with
Rabbit, Rat, Human, Pig, Mouse, Dog, Bovine, Horse
Application
IHC, WB
$229.00
  pAb OAAB04209 PRKAA1 Antibody (OAAB04209)
Reacts with
Human
Application
WB, FC, IHC
$289.00
  pAb ARP58120_P050 JMJD5 antibody - middle region (ARP58120_P050)
Reacts with
Human, Mouse, Rabbit, Rat, Dog, Horse, Bovine, Zebrafish, Pig, Guinea pig
Application
CHIP, WB
$289.00
  pAb ARP39073_T100 CBX6 antibody - N-terminal region (ARP39073_T100)
Reacts with
Zebrafish, Bovine, Human, Mouse, Dog, Rat, Pig, Horse, Rabbit, Guinea pig
Application
IHC, WB
$229.00
  pAb ARP32481_T100 CBX5 antibody - middle region (ARP32481_T100)
Reacts with
Sheep, Bovine, Pig, Horse, Rabbit, Rat, Human, Dog, Mouse
Application
IHC, WB
$229.00
  pAb ARP40185_T100 PRMT5 antibody - N-terminal region (ARP40185_T100)
Reacts with
Human, Pig, Rat, Dog, Horse, Rabbit, Guinea pig, Mouse, Bovine, Zebrafish
Application
IHC, WB
$229.00
  pAb ARP38223_P050 SMARCD2 antibody - C-terminal region (ARP38223_P050)
Reacts with
Human, Bovine, Dog, Pig, Horse, Rabbit, Mouse, Rat, Guinea pig, Zebrafish
Application
IHC, WB
$289.00
  pAb ARP65151_P050 TNK1 antibody - C-terminal region (ARP65151_P050)
Reacts with
Yeast, Human, Pig, Guinea pig, Rabbit
Application
WB
$289.00
  pAb ARP39004_P050 IKZF3 antibody - N-terminal region (ARP39004_P050)
Reacts with
Human, Bovine, Dog, Pig, Rabbit, Rat, Mouse
Application
IHC, WB
$289.00
  pAb ARP38820_P050 CTCF antibody - N-terminal region (ARP38820_P050)
Reacts with
Dog, Horse, Rabbit, Rat, Guinea pig, Human, Mouse, Bovine
Application
CHIP, WB
$289.00
  pAb ARP34484_P050 SMARCA2 antibody - middle region (ARP34484_P050)
Reacts with
Bovine, Human, Dog, Rat, Pig, Horse, Rabbit, Guinea pig, Zebrafish, Mouse
Application
WB, IHC
$289.00
  pAb ARP31931_P050 HDAC2 antibody - middle region (ARP31931_P050)
Reacts with
Rat, Human, Bovine, Pig, Horse, Guinea pig, Mouse, Dog, Rabbit
Application
CHIP, IHC, WB
$289.00
  pAb ARP39521_P050 TEAD1 antibody - C-terminal region (ARP39521_P050)
Reacts with
Human, Zebrafish, Pig, Bovine, Mouse, Rat, Dog, Horse, Rabbit, Guinea pig
Application
IHC, WB
$289.00
  pAb ARP64034_P050 SFTPA2 antibody - N-terminal region (ARP64034_P050)
Reacts with
Human, Bovine, Pig, Sheep, Dog, Goat, Rat, Horse, Guinea pig, Rabbit, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP46356_P050 LMNB2 antibody - N-terminal region (ARP46356_P050)
Reacts with
Bovine, Horse, Guinea pig, Human, Mouse, Rat, Rabbit
Application
WB
$289.00
  pAb ARP42210_T100 RAD23A antibody - N-terminal region (ARP42210_T100)
Reacts with
Dog, Pig, Horse, Rat, Guinea pig, Human, Mouse, Rabbit, Bovine
Application
IHC, WB
$229.00
  pAb ARP58280_P050 H2AFX antibody - N-terminal region (ARP58280_P050)
Reacts with
Zebrafish, Rat, Dog, Guinea pig, Human, Mouse, Bovine, Horse
Application
WB
$289.00
  pAb ARP40413_P050 PPP1R10 antibody - N-terminal region (ARP40413_P050)
Reacts with
Mouse, Rat, Bovine, Dog, Pig, Human, Horse, Rabbit, Guinea pig
Application
IF, WB
$289.00

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Showing 1 - 30 of 740