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Catalog No: ARP32470_T100
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ARP32470_T100
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Datasheets/ManualsPrintable datasheet for anti-SUV39H1 (ARP32470_T100) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C terminal region of human SUV39H1
PurificationProtein A purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%
Peptide SequenceSynthetic peptide located within the following region: FDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYLF
Concentration1.0 mg/ml
Blocking PeptideFor anti-SUV39H1 (ARP32470_T100) antibody is Catalog # AAP32470 (Previous Catalog # AAPP03468)
Sample Type Confirmation

SUV39H1 is supported by BioGPS gene expression data to be expressed in HepG2

ReferenceFrontelo,P., et al., (2004) Oncogene 23 (30), 5242-5251
Publications

Enhanced levels of microRNA-125b in vascular smooth muscle cells of diabetic db/db mice lead to increased inflammatory gene expression by targeting the histone methyltransferase Suv39h1. Diabetes. 59, 2904-15 (2010). 20699419

Description
Gene SymbolSUV39H1
Gene Full NameSuppressor of variegation 3-9 homolog 1 (Drosophila)
Alias SymbolsMG44, KMT1A, SUV39H, H3-K9-HMTase 1
NCBI Gene Id6839
Protein NameHistone-lysine N-methyltransferase SUV39H1
Description of TargetSUV39H1, a human homolog of the Drosophila position effect variegation modifier Su(var)3-9 and of the S. pombe silencing factor clr4, encodes a heterochromatic protein that transiently accumulates at centromeric positions during mitosis.This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Uniprot IDO43463
Protein Accession #NP_003164
Nucleotide Accession #NM_003173
Protein Size (# AA)412
Molecular Weight48kDa
Protein InteractionsLZTS2; CEP70; HOOK2; CBX5; KRTAP10-7; HIST2H3A; CDCA4; KLHDC4; GTPBP2; ZNF581; ZCCHC17; CRBN; ING4; DCAF8; KLF15; KLHL20; PHF19; IL16; IGFBP4; ID2; ID1; HOXC4; HOXA1; FYN; FUS; EZH2; CLK3; ATP6V1B1; ATF3; GTF2H2C_2; H3F3C; LHX8; STX19; C17orf82; ZNF829; C
  1. What is the species homology for "SUV39H1 Antibody - C-terminal region (ARP32470_T100)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish".

  2. How long will it take to receive "SUV39H1 Antibody - C-terminal region (ARP32470_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "SUV39H1 Antibody - C-terminal region (ARP32470_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "SUV39H1 Antibody - C-terminal region (ARP32470_T100)"?

    This target may also be called "MG44, KMT1A, SUV39H, H3-K9-HMTase 1" in publications.

  5. What is the shipping cost for "SUV39H1 Antibody - C-terminal region (ARP32470_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "SUV39H1 Antibody - C-terminal region (ARP32470_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "SUV39H1 Antibody - C-terminal region (ARP32470_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "48kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "SUV39H1 Antibody - C-terminal region (ARP32470_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "SUV39H1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "SUV39H1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "SUV39H1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "SUV39H1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "SUV39H1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "SUV39H1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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