SAP30 Antibody - N-terminal region (ARP38392_T100)

Catalog No: ARP38392_T100

WB Suggested Anti-SAP30 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:312500
Positive Control: Transfected 293T

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SAP30
• Purification: Protein A purified
• Predicted Homology Based on Immunogen Sequence: Cow: 86%; Dog: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%
• Peptide Sequence: Synthetic peptide located within the following region: MNGFTPDEMSRGGDAAAAVAAVVAAAAAAASAGNGTGAGTGAEVPGAGAV
• Concentration: 1.0 mg/ml
• Blocking Peptide: For anti-SAP30 (ARP38392_T100) antibody is Catalog # AAP38392 (Previous Catalog # AAPP20578)
• Subunit: SAP30
• Reference: Sironi,E., (2004) J. Cutan. Pathol. 31 (4), 318-322

Target Info

• Gene Symbol: SAP30
• Gene Full Name: Sin3A-associated protein, 30kDa
• NCBI Gene Id: 8819
• Protein Name: Histone deacetylase complex subunit SAP30
• Description of Target: Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP30 is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3.
• Uniprot ID: O75446
• Protein Accession #: NP_003855
• Nucleotide Accession #: NM_003864
• Protein Size (# AA): 220
• Molecular Weight: 23kDa
• Protein Interactions: HDAC3; CUL4B; DDB1; HDAC1; SIN3A; UBC; HDAC2; BRMS1L; ING1; ARID4A; SAMSN1; ZNF395; UBASH3B; RBBP7; RBBP4; CHD4; ALL1; TAF6; SMARCA2; SAP25; RBP1; HIST2H2BE; PCBD1; ID3; SAP30BP; HIST2H4A; HBP1; HIST1H2AL; BRMS1; CIR1; HIST3H3; NCOR1; NCOR2; MXD1; YY1; HT