Catalog No: ARP34468_T100
Price: $0.00
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ARP34468_T100
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Datasheets/ManualsPrintable datasheet for anti-MIER1 (ARP34468_T100) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human MIER1
PurificationProtein A purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Peptide SequenceSynthetic peptide located within the following region: RRTGDEKGVEAIPEGSHIKDNEQALYELVKCNFDTEEALRRLRF
Concentration1.0 mg/ml
Blocking PeptideFor anti-MIER1 (ARP34468_T100) antibody is Catalog # AAP34468 (Previous Catalog # AAPY00430)
ReferencePaterno, G.D., et al., (1998) Gene 222 (1), 77-82
Gene SymbolMIER1
Gene Full NameMesoderm induction early response 1 homolog (Xenopus laevis)
Alias SymbolsER1, MI-ER1
NCBI Gene Id57708
Protein NameMesoderm induction early response protein 1
Description of TargetThe association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).
Uniprot IDQ8NES5
Protein Accession #NP_065999
Nucleotide Accession #NM_020948
Protein Size (# AA)536
Molecular Weight49kDa
Protein InteractionsTMEM171; SOX2; HDAC2; HDAC1; EHMT2; CDYL; TUBB1; APP; ELAVL1; UBC; CREBBP; SP1;
  1. What is the species homology for "MIER1 Antibody - middle region (ARP34468_T100)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish".

  2. How long will it take to receive "MIER1 Antibody - middle region (ARP34468_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "MIER1 Antibody - middle region (ARP34468_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "MIER1 Antibody - middle region (ARP34468_T100)"?

    This target may also be called "ER1, MI-ER1" in publications.

  5. What is the shipping cost for "MIER1 Antibody - middle region (ARP34468_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "MIER1 Antibody - middle region (ARP34468_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "MIER1 Antibody - middle region (ARP34468_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "49kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "MIER1 Antibody - middle region (ARP34468_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "MIER1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "MIER1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "MIER1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "MIER1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "MIER1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "MIER1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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