FKBP3 Antibody - C-terminal region (ARP54612_P050)

Catalog No: ARP54612_P050

WB Suggested Anti-FKBP3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysateFKBP3 is supported by BioGPS gene expression data to be expressed in Jurkat

Host: Rabbit
Target Name: FKBP3
Sample Type: Human MCF7
Antibody Dilution: 1.0ug/mlFKBP3 is supported by BioGPS gene expression data to be expressed in MCF7

Host: Rabbit
Target Name: FKBP3
Sample Type: Human 721_B
Antibody Dilution: 1.0ug/mlFKBP3 is supported by BioGPS gene expression data to be expressed in 721_B

Host: Rabbit
Target Name: FKBP3
Sample Type: Human Hela
Antibody Dilution: 1.0ug/mlFKBP3 is supported by BioGPS gene expression data to be expressed in HeLa

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FKBP3
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
• Peptide Sequence: Synthetic peptide located within the following region: EALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-FKBP3 (ARP54612_P050) antibody is Catalog # AAP54612 (Previous Catalog # AAPP31403)
• Sample Type Confirmation:

  FKBP3 is supported by BioGPS gene expression data to be expressed in 721_B, HeLa, Jurkat, MCF7

• Reference: Meng,X., Biochem. Genet. 40 (9-10), 303-310 (2002)

Target Info

• Gene Symbol: FKBP3
• Gene Full Name: FK506 binding protein 3, 25kDa
• Alias Symbols: FKBP-3, FKBP25, PPIase, FKBP-25
• NCBI Gene Id: 2287
• Protein Name: Peptidyl-prolyl cis-trans isomerase FKBP3
• Description of Target: FKBP3 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP3 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
• Uniprot ID: Q00688
• Protein Accession #: NP_002004
• Nucleotide Accession #: NM_002013
• Protein Size (# AA): 224
• Molecular Weight: 25kDa
• Protein Interactions: UBC; EDC4; IGF2BP3; SYNCRIP; SEC16A; EIF2B2; EIF2B3; DYNLL1; RFC4; YBX1; NMT1; KRT18; ILF2; HNRNPU; HNRNPA2B1; DDX1; ABCF1; MAP1S; C14orf166; DIMT1; NELFB; SRPK1; FBXO25; BARD1; MYH10; PACSIN3; LRRFIP1; TIMELESS; Nedd4; NEDD4L; CALM1; HDAC2; HDAC1; YY1; C