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Catalog No: ARP32917_T100
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ARP32917_T100
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Datasheets/ManualsPrintable datasheet for anti-DMAP1 (ARP32917_T100) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human DMAP1
PurificationProtein A purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
Peptide SequenceSynthetic peptide located within the following region: DAWTKAETDHLFDLSRRFDLRFVVIHDRYDHQQFKKRSVEDLKERYYHIC
Concentration1.0 mg/ml
Blocking PeptideFor anti-DMAP1 (ARP32917_T100) antibody is Catalog # AAP32917 (Previous Catalog # AAPP03941)
ReferenceOh,J.H., et al., (2005) Mamm. Genome 16 (12), 942-954
Gene SymbolDMAP1
Gene Full NameDNA methyltransferase 1 associated protein 1
Alias SymbolsEAF2, SWC4, MEAF2, DNMAP1, DNMTAP1
NCBI Gene Id55929
Protein NameDNA methyltransferase 1-associated protein 1
Description of TargetDMAP1 is a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.
Uniprot IDQ9NPF5
Protein Accession #NP_001029196
Nucleotide Accession #NM_001034024
Protein Size (# AA)467
Molecular Weight51kDa
Protein InteractionsSOX2; UBC; RNF2; HECW2; RUVBL2; SRCAP; CFDP1; RUVBL1; DENR; VPS72; TOMM34; TSG101; H2AFZ; DAXX; SMARCAD1; SUMO2; EPC1; ACTL6A; ACTA1; PPP2R2D; ING3; MORF4L1; BRD8; KAT5; TRRAP; YEATS4; EP400; EPC2; MYC; MAX; ACTG1; ACTB; MRGBP; MORF4L2; MNAT1; HDAC1; tat;
  1. What is the species homology for "DMAP1 Antibody - N-terminal region (ARP32917_T100)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish".

  2. How long will it take to receive "DMAP1 Antibody - N-terminal region (ARP32917_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "DMAP1 Antibody - N-terminal region (ARP32917_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "DMAP1 Antibody - N-terminal region (ARP32917_T100)"?

    This target may also be called "EAF2, SWC4, MEAF2, DNMAP1, DNMTAP1" in publications.

  5. What is the shipping cost for "DMAP1 Antibody - N-terminal region (ARP32917_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "DMAP1 Antibody - N-terminal region (ARP32917_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "DMAP1 Antibody - N-terminal region (ARP32917_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "51kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "DMAP1 Antibody - N-terminal region (ARP32917_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "DMAP1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "DMAP1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "DMAP1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "DMAP1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "DMAP1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "DMAP1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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