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Catalog No: ARP30357_T100
Price: $0.00
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ARP30357_T100
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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Datasheets/ManualsPrintable datasheet for anti-TRAF6 (ARP30357_T100) antibody
Product Info
Tested Species ReactivityHuman, Mouse
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Horse, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C-terminal region of Human TRAF6
Predicted Homology Based on Immunogen SequenceCow: 100%; Horse: 100%; Human: 100%; Mouse: 91%; Pig: 100%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: FGYVTFMHLEALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDA
Concentration1.0 mg/ml
Blocking PeptideFor anti-TRAF6 (ARP30357_T100) antibody is Catalog # AAP30357
Gene SymbolTRAF6
Alias SymbolsRNF85, MGC:3310
NCBI Gene Id7189
Description of TargetTRAF6 is an E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, AKT1 and AKT2. It also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF-kappa-B and JUN. It may be essential for the formation of functional osteoclasts. It seems to also play a role in dendritic cells (DCs) maturation and/or activation. It represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor. It regulates osteoclast differentiation by mediating the activation of adapter protein complex 1 (AP-1) and NF-kappa-B, in response to RANK-L stimulation.
Uniprot IDQ9Y4K3
Protein Accession #NP_004611
Nucleotide Accession #NM_004620
Protein Size (# AA)522
Molecular Weight57kDa
Protein InteractionsYES1; UBE2V1; UBE2N; UBE2L3; UBE2E1; UBE2D2; UBE2D1; POLI; UBC; IL1R1; EDARADD; PLEKHF2; LAT; TRAF3IP2; PPP4R1; USP2; IKBKG; TRAF6; TRAF5; TRAF2; TRAF1; CNTN2; SYK; VPS52; PSEN1; LGMN; MEOX2; MCL1; CANX; nef; TAB2; OTUD7A; GTF2I; KRAS; DCBLD2; MAP3K7; EIF
  1. What is the species homology for "TRAF6 Antibody - C-terminal region (ARP30357_T100)"?

    The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Horse, Pig, Rabbit".

  2. How long will it take to receive "TRAF6 Antibody - C-terminal region (ARP30357_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "TRAF6 Antibody - C-terminal region (ARP30357_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "TRAF6 Antibody - C-terminal region (ARP30357_T100)"?

    This target may also be called "RNF85, MGC:3310" in publications.

  5. What is the shipping cost for "TRAF6 Antibody - C-terminal region (ARP30357_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "TRAF6 Antibody - C-terminal region (ARP30357_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "TRAF6 Antibody - C-terminal region (ARP30357_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "57kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "TRAF6 Antibody - C-terminal region (ARP30357_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "TRAF6"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "TRAF6"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "TRAF6"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "TRAF6"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "TRAF6"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "TRAF6"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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