RBBP5 Antibody - middle region (ARP34206_P050)

Catalog No: ARP34206_P050

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WB Suggested Anti-RBBP5 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: HepG2 cell lysate

Host: Rabbit
Target Name: RBBP5
Sample Type: Human Adult Placenta
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: RBBP5
Sample Type: Human MCF7
Antibody Dilution: 1.0ug/mlRBBP5 is supported by BioGPS gene expression data to be expressed in MCF7

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RBBP5
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: GASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSK
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-RBBP5 (ARP34206_P050) antibody is Catalog # AAP34206 (Previous Catalog # AAPP05521)
• Sample Type Confirmation:

  RBBP5 is supported by BioGPS gene expression data to be expressed in MCF7

• Reference: Olsen,J.V., (2006) Cell 127 (3), 635-648

Target Info

• Gene Symbol: RBBP5
• Gene Full Name: Retinoblastoma binding protein 5
• Alias Symbols: RBQ3, SWD1
• NCBI Gene Id: 5929
• Protein Name: Retinoblastoma-binding protein 5
• Description of Target: RBBP5 contains 6 WD repeats. It binds preferentially to underphosphorylated retinoblastoma protein. The protein encoded by this gene is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1 AU099032.1 13-13 2-26 CD710496.1 39-63 27-567 BC053856.1 17-557 568-1604 BC037284.2 540-1576 1605-2978 BC053856.1 1595-2968 2979-2979 BC037284.2 2838-2838 2980-2992 AA235403.1 1-13 2993-3136 BC037284.2 2851-2994 3137-3318 BC053856.1 3125-3306 3319-3334 BC037284.2 3177-3192 3335-3342 BG392257.1 177-184 3343-3587 BC037284.2 3200-3444 3588-3683 CB133829.1 341-436
• Uniprot ID: Q15291
• Protein Accession #: NP_005048
• Nucleotide Accession #: NM_005057
• Protein Size (# AA): 538
• Molecular Weight: 59kDa
• Protein Interactions: CXXC1; SETD1A; ASH2L; PPARG; KMT2A; KMT2D; SENP3; UBE2I; UBC; SUMO2; Fbxl16; KDM6B; KDM6A; SMARCD1; KLC2; SRRT; DHX38; SMARCE1; SMARCD2; HCFC1; SMARCC1; MEN1; USF1; WDR5; ELAVL1; ESR1; KANSL1; DPY30; KDM4B; KMT2B; PSMA3; CTBP1; TBK1; CDC73; HIST3H3; PYGO2