KCNQ1 Antibody - N-terminal region (ARP35529_T100)

Catalog No: ARP35529_T100

WB Suggested Anti-KCNQ1 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate

Lanes:
100 ug CHO cell lysate
Primary Antibody Dilution:
1:1000
Secondary Antibody:
Goat anti-rabbit HRP
Secondary Antibody Dilution:
1:25000
Gene Name:
KCNQ1
Submitted by:
Anonymous

Host: Mouse
Target Name: KCNQ1
Sample Tissue: Mouse Brain
Antibody Dilution: 1ug/ml

Product Info

• Tested Species Reactivity: Human, Mouse, Hamster
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNQ1
• Purification: Protein A purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
• Peptide Sequence: Synthetic peptide located within the following region: IVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGS
• Concentration: 1.0 mg/ml
• Blocking Peptide: For anti-KCNQ1 (ARP35529_T100) antibody is Catalog # AAP35529 (Previous Catalog # AAPP06769)
• Reference: Du,LP., et al., (2005) Biochem Biophys Res Commun. 332(3), 677-87

Target Info

• Gene Symbol: KCNQ1
• Gene Full Name: Potassium voltage-gated channel, KQT-like subfamily, member 1
• Alias Symbols: LQT, RWS, WRS, LQT1, SQT2, ATFB1, ATFB3, JLNS1, KCNA8, KCNA9, Kv1.9, Kv7.1, KVLQT1
• NCBI Gene Id: 3784
• Protein Name: Potassium voltage-gated channel subfamily KQT member 1
• Description of Target: KCNQ1 encodes a protein for a voltage-gated potassium channel required for the repolarization phase of the cardiac action potential. The gene product can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in KCNQ1 are associated with hereditary long QT syndrome, Romano-Ward syndrome, Jervell and Lange-Nielsen syndrome and familial atrial fibrillation.
• Uniprot ID: P51787-2
• Protein Accession #: NP_861463
• Nucleotide Accession #: NM_181798
• Protein Size (# AA): 549
• Molecular Weight: 60kDa
• Protein Interactions: ATP4A; NEDD4L; AP2M1; USP2; UBC; NEDD4; PRKACA; KCNE1; HSPA4; KCNE4; AKAP9; KCNE2; TRAF6; KCNQ2; PRKAR2A; PPP1CA;