HNRNPU Antibody - C-terminal region (ARP40518_P050)

Catalog No: ARP40518_P050

WB Suggested Anti-HNRNPU Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: ACHN cell lysateHNRNPU is strongly supported by BioGPS gene expression data to be expressed in Human ACHN cells

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HNRNPU
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: EITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQF
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-HNRNPU (ARP40518_P050) antibody is Catalog # AAP40518 (Previous Catalog # AAPP22285)
• Sample Type Confirmation:

  HNRNPU is strongly supported by BioGPS gene expression data to be expressed in ACHN

Target Info

• Gene Symbol: HNRNPU
• Gene Full Name: Heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
• Alias Symbols: SAFA, DEE54, HNRPU, SAF-A, U21.1, pp120, EIEE54, GRIP120, hnRNP U, HNRNPU-AS1
• NCBI Gene Id: 3192
• Protein Name: Heterogeneous nuclear ribonucleoprotein U
• Description of Target: HNRNPU belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. HNRNPU contains a RNA binding domain and scaffold-associated region (SAR)-specific bipartite DNA-binding domain. This protein is also thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes. During apoptosis, this protein is cleaved in a caspase-dependent way. But this cleavage does not affect the function of the encoded protein in RNA metabolism.
• Uniprot ID: Q00839
• Protein Accession #: NP_114032
• Nucleotide Accession #: NM_031844
• Protein Size (# AA): 825
• Molecular Weight: 90kDa
• Protein Interactions: FBXW11; FUS; HUWE1; BTRC; UBC; TUBG1; TP53; AURKA; MAGED2; TUBGCP3; CEP57; AURKB; SUMO2; SUMO3; CEP70; CEP76; MDM2; LGALS3BP; EMD; HAUS2; TUBGCP4; CEP250; NEDD1; STAU1; IVNS1ABP; LGR4; ERG; RPA3; RPA2; RPA1; WWOX; RNF2; SHFM1; EED; rev; RPS29; RPS27; RPS6