SF3A3 Antibody - middle region (ARP40684_P050)

Catalog No: ARP40684_P050

WB Suggested Anti-SF3A3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: 721_B cell lysateSF3A3 is supported by BioGPS gene expression data to be expressed in 721_B

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SF3A3
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 91%
• Peptide Sequence: Synthetic peptide located within the following region: THENVQRKQARTGEEREEEEEEQISESESEDEENEIIYNPKNLPLGWDGK
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-SF3A3 (ARP40684_P050) antibody is Catalog # AAP40684 (Previous Catalog # AAPP33394)
• Sample Type Confirmation:

  SF3A3 is supported by BioGPS gene expression data to be expressed in 721_B

• Subunit: 3
• Reference: Ewing,R.M., Mol. Syst. Biol. 3, 89 (2007)

Target Info

• Gene Symbol: SF3A3
• Gene Full Name: Splicing factor 3a, subunit 3, 60kDa
• Alias Symbols: PRP9, PRPF9, SAP61, SF3a60
• NCBI Gene Id: 10946
• Protein Name: Splicing factor 3A subunit 3
• Description of Target: SF3A3 is the subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP.This This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Uniprot ID: Q12874
• Protein Accession #: NP_006793
• Nucleotide Accession #: NM_006802
• Protein Size (# AA): 501
• Molecular Weight: 59kDa
• Protein Interactions: TRIM69; HUWE1; ZNF212; TADA2A; FUS; UBC; NEDD8; MDM2; WWOX; RNF2; SUZ12; EED; rev; APBB1; ACTN1; ACTN4; STAM2; HGS; SNRPB; CDAN1; PRPF40A; WBP4; TCERG1; UBD; SF3A1; FN1; gag-pol; PRMT5; PRPF19; PRPF31; SF3B1; SF3B3; SF3B4; HNRNPR; DDX46; TOX4; DDX23; PRPF